Literature DB >> 24874405

[Small cell lung cancer associated with paraneoplastic bullous pemphigoid].

N Lakhdar1, W El Khattabi2, M Lahroussi2, H Afif2, A Aichane2.   

Abstract

The broncho-pulmonary small cell carcinoma is the most common cancer provider paraneoplastic syndrome especially neurological and endocrine but also cutaneous syndrome. Paraneoplastic dermatosis do not result from a direct extension of cancer and are not metastases, but their presence is suggestive of an underlying tumor. The evolution of the dermatosis is parallel to that of cancer: treating cancer results in the regression of cutaneous manifestations. We report an observation of a 44-year-old smoker, who was hospitalized for a tissue excavated process associated with bullous dermatosis. The transmural puncture biopsy finds small cell carcinoma. The skin biopsy objective bullous pemphigoid. The evolution under chemotherapy was marked regression of bullous lesions and the patient died later after metastatic extension. Cutaneous paraneoplastic syndrome appears only in a minority of cancer patients, but its recognition is very important for early diagnosis.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Bullous pemphigoid; Cancer pulmonaire à petites cellules; Paraneoplastic syndrome; Pemphigoïde bulleuse; Small cell lung cancer; Syndrome paranéoplasique

Mesh:

Year:  2014        PMID: 24874405     DOI: 10.1016/j.pneumo.2013.11.011

Source DB:  PubMed          Journal:  Rev Pneumol Clin        ISSN: 0761-8417


  2 in total

1.  [Bullous pemphigoid revealing bronchial carcinoma].

Authors:  Hicham Janah; Meryem Mahhou; Hicham Souhi; Adil Zegmout; Hicham Naji-Amrani; Mohamed Raoufi; Hanane Elouazzani; Ismail Abderrahmani Rhorfi; Ahmed Abid
Journal:  Pan Afr Med J       Date:  2014-09-19

2.  Bullous pemphigoid associated with squamous cell lung carcinoma showing remarkable response to carboplatin-based chemotherapy:  a case report.

Authors:  Prajwol Shrestha; Mathew K George; Sweta Baidya; Sunil K Rai
Journal:  J Med Case Rep       Date:  2022-05-05
  2 in total

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