Saif Khan1, Narender Dev Gupta1. 1. Department of Periodontics and Community Dentistry, Faculty of Medicine, Dr. Z. A. Dental College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Sir,In reference to letter to the editor by Joob and Wiwanitkit[1] regarding our case report of acute gingival bleeding as a complication of dengue hemorrhagic fever published in your journal dengue.[2] He has emphasized the fact that dengue fever should be included in differential diagnosis of acute gingival bleeding, which is manifested as a result of thrombocytopenia in dengue.[12] We would also like to draw your attention toward falciparum malaria as one more probable cause of thrombocytopenia, which may manifest as acute gingival bleeding.[3] As malaria can cause thrombocytopenia via immune-mediated mechanisms.[4] Therefore, falciparum malaria should also be considered in differential diagnosis of acute gingival bleeding, as both these diseases are mosquito borne tropical diseases and very much relevant in this context.[23]
Authors: J G Kelton; J Keystone; J Moore; G Denomme; E Tozman; M Glynn; P B Neame; J Gauldie; J Jensen Journal: J Clin Invest Date: 1983-04 Impact factor: 14.808