Literature DB >> 24871961

Mouse studies on inhibitors of Plasmodium falciparum Hsp90: progress and challenges.

Abebe Genetu Bayih1, Dylan R Pillai1.   

Abstract

This review highlights studies conducted in murine models to evaluate the efficacy of compounds targeting Heat shock protein (Hsp) 90 of malaria. Both advances achieved and limitations that exist are highlighted.

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Year:  2014        PMID： 24871961     DOI： 10.1017/S0031182014000754

Source DB:  PubMed          Journal:  Parasitology        ISSN： 0031-1820            Impact factor:   3.234


  4 in total

1.  In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin.

Authors:  Abebe Genetu Bayih; Asongna Folefoc; Abu Naser Mohon; Scott Eagon; Marc Anderson; Dylan R Pillai
Journal:  Malar J       Date:  2016-12-01       Impact factor: 2.979

2.  Synergistic Action between PfHsp90 Inhibitor and PfRad51 Inhibitor Induces Elevated DNA Damage Sensitivity in the Malaria Parasite.

Authors:  Wahida Tabassum; Priyanka Singh; Niranjan Suthram; Sunanda Bhattacharyya; Mrinal Kanti Bhattacharyya
Journal:  Antimicrob Agents Chemother       Date:  2021-08-17       Impact factor: 5.191

3.  Potential Interaction of Plasmodium falciparum Hsp60 and Calpain.

Authors:  Seon-Ju Yeo; Dong-Xu Liu; Hyun Park
Journal:  Korean J Parasitol       Date:  2015-12-31       Impact factor: 1.341

4.  Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors.

Authors:  Claribel Murillo-Solano; Chunmin Dong; Cecilia G Sanchez; Juan C Pizarro
Journal:  Malar J       Date:  2017-07-19       Impact factor: 2.979
  4 in total

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