Literature DB >> 24871629

Vascular induction of a disintegrin and metalloprotease 17 by angiotensin II through hypoxia inducible factor 1α.

Takashi Obama1, Takehiko Takayanagi1, Tomonori Kobayashi1, Allison M Bourne1, Katherine J Elliott1, Martine Charbonneau2, Claire M Dubois2, Satoru Eguchi3.   

Abstract

BACKGROUND: A disintegrin and metalloprotease 17 (ADAM17) is a membrane-spanning metalloprotease overexpressed in various cardiovascular diseases such as hypertension and atherosclerosis. However, little is known regarding the regulation of ADAM17 expression in the cardiovascular system. Here, we test our hypothesis that angiotensin II induces ADAM17 expression in the vasculature.
METHODS: Cultured vascular smooth muscle cells were stimulated with 100 nM angiotensin II. Mice were infused with 1 μg/kg/minute angiotensin II for 2 weeks. ADAM17 expression was evaluated by a promoter-reporter construct, quantitative polymerase chain reaction, immunoblotting, and immunohistochemistry.
RESULTS: In vascular smooth muscle cells, angiotensin II increased ADAM17 protein expression, mRNA, and promoter activity. We determined that the angiotensin II response involves hypoxia inducible factor 1α and a hypoxia responsive element. In angiotensin II-infused mice, marked induction of ADAM17 and hypoxia inducible factor 1α was seen in vasculatures in heart and kidney, as well as in aortae, by immunohistochemistry.
CONCLUSIONS: Angiotensin II induces ADAM17 expression in the vasculatures through a hypoxia inducible factor 1α-dependent transcriptional upregulation, potentially contributing to end-organ damage in the cardiovascular system. © American Journal of Hypertension, Ltd 2014. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  blood pressure; epidermal growth factor receptor; hypertension; renin–angiotensin system; signal transduction; tumor necrosis factor α converting enzyme; vascular biology.

Mesh：

Substances：

Year:  2014        PMID： 24871629      PMCID： PMC4318952          DOI： 10.1093/ajh/hpu094

Source DB:  PubMed          Journal:  Am J Hypertens        ISSN： 0895-7061            Impact factor:   2.689


  20 in total

1.  Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells.

Authors:  D E Richard; E Berra; J Pouyssegur
Journal:  J Biol Chem       Date:  2000-09-01       Impact factor: 5.157

2.  Post-transcriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors.

Authors:  Belén Santiago-Josefat; Cary Esselens; Joan Josep Bech-Serra; Joaquín Arribas
Journal:  J Biol Chem       Date:  2007-01-16       Impact factor: 5.157

3.  The TNF alpha converting enzyme (TACE/ADAM17) is expressed in the atherosclerotic lesions of apolipoprotein E-deficient mice: possible contribution to elevated plasma levels of soluble TNF alpha receptors.

Authors:  Matthias Canault; Franck Peiretti; Francis Kopp; Bernadette Bonardo; Marie-France Bonzi; Jean-Christophe Coudeyre; Marie-Christine Alessi; Irène Juhan-Vague; Gilles Nalbone
Journal:  Atherosclerosis       Date:  2005-10-07       Impact factor: 5.162

4.  Caveolin-1 negatively regulates a metalloprotease-dependent epidermal growth factor receptor transactivation by angiotensin II.

Authors:  Akira Takaguri; Heigoro Shirai; Keita Kimura; Akinari Hinoki; Kunie Eguchi; MaryEllen Carlile-Klusacek; Baohua Yang; Victor Rizzo; Satoru Eguchi
Journal:  J Mol Cell Cardiol       Date:  2010-12-21       Impact factor: 5.000

5.  ADAM17 mediates epidermal growth factor receptor transactivation and vascular smooth muscle cell hypertrophy induced by angiotensin II.

Authors:  Haruhiko Ohtsu; Peter J Dempsey; Gerald D Frank; Eugen Brailoiu; Sadaharu Higuchi; Hiroyuki Suzuki; Hidekatsu Nakashima; Kunie Eguchi; Satoru Eguchi
Journal:  Arterioscler Thromb Vasc Biol       Date:  2006-07-13       Impact factor: 8.311

6.  Hypoxia-inducible factor mediates hypoxic and tumor necrosis factor alpha-induced increases in tumor necrosis factor-alpha converting enzyme/ADAM17 expression by synovial cells.

Authors:  Martine Charbonneau; Kelly Harper; Francine Grondin; Manuela Pelmus; Patrick P McDonald; Claire M Dubois
Journal:  J Biol Chem       Date:  2007-09-19       Impact factor: 5.157

7.  Polymorphisms of the tumor necrosis factor-alpha (TNF) and the TNF-alpha converting enzyme (TACE/ADAM17) genes in relation to cardiovascular mortality: the AtheroGene study.

Authors:  P E Morange; D A Tregouet; T Godefroy; N Saut; C Bickel; H J Rupprecht; K Lackner; S Barbaux; O Poirier; F Peiretti; G Nalbone; I Juhan-Vague; S Blankenberg; L Tiret
Journal:  J Mol Med (Berl)       Date:  2008-07-04       Impact factor: 4.599

8.  Differential regulation of hypoxia-inducible factor-1 through receptor tyrosine kinase transactivation in vascular smooth muscle cells.

Authors:  Marie-Claude Lauzier; Elisabeth L Pagé; Maude D Michaud; Darren E Richard
Journal:  Endocrinology       Date:  2007-05-17       Impact factor: 4.736

9.  Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis.

Authors:  Xiang Wang; Tatsujiro Oka; Fung L Chow; Stephan B Cooper; Jeff Odenbach; Gary D Lopaschuk; Zamaneh Kassiri; Carlos Fernandez-Patron
Journal:  Hypertension       Date:  2009-07-06       Impact factor: 10.190

10.  MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation.

Authors:  Yunhui Cheng; Xiaojun Liu; Jian Yang; Ying Lin; Da-Zhong Xu; Qi Lu; Edwin A Deitch; Yuqing Huo; Ellise S Delphin; Chunxiang Zhang
Journal:  Circ Res       Date:  2009-06-18       Impact factor: 17.367
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  12 in total

1.  High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells.

Authors:  Renzhong Li; Lalita Uttarwar; Bo Gao; Martine Charbonneau; Yixuan Shi; John S D Chan; Claire M Dubois; Joan C Krepinsky
Journal:  J Biol Chem       Date:  2015-07-14       Impact factor: 5.157

2.  Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin II.

Authors:  Steven J Forrester; Katherine J Elliott; Tatsuo Kawai; Takashi Obama; Michael J Boyer; Kyle J Preston; Zhen Yan; Satoru Eguchi; Victor Rizzo
Journal:  Hypertension       Date:  2016-11-28       Impact factor: 10.190

Review 3.  Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.

Authors:  Steven J Forrester; George W Booz; Curt D Sigmund; Thomas M Coffman; Tatsuo Kawai; Victor Rizzo; Rosario Scalia; Satoru Eguchi
Journal:  Physiol Rev       Date:  2018-07-01       Impact factor: 37.312

4.  ADAM and ADAMTS disintegrin and metalloproteinases as major factors and molecular targets in vascular malfunction and disease.

Authors:  HaiFeng Yang; Raouf A Khalil
Journal:  Adv Pharmacol       Date:  2022-01-24

5.  Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.

Authors:  Takehiko Takayanagi; Tatsuo Kawai; Steven J Forrester; Takashi Obama; Toshiyuki Tsuji; Yamato Fukuda; Katherine J Elliott; Douglas G Tilley; Robin L Davisson; Joon-Young Park; Satoru Eguchi
Journal:  Hypertension       Date:  2015-04-27       Impact factor: 10.190

6.  Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular System.

Authors:  Steven J Forrester; Tatsuo Kawai; Shannon O'Brien; Walter Thomas; Raymond C Harris; Satoru Eguchi
Journal:  Annu Rev Pharmacol Toxicol       Date:  2015-11-09       Impact factor: 13.820

Review 7.  Contribution of ADAM17 and related ADAMs in cardiovascular diseases.

Authors:  Tatsuo Kawai; Katherine J Elliott; Rosario Scalia; Satoru Eguchi
Journal:  Cell Mol Life Sci       Date:  2021-02-11       Impact factor: 9.207

8.  Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells.

Authors:  Jose L Morgado-Pascual; Sandra Rayego-Mateos; Jose M Valdivielso; Alberto Ortiz; Jesus Egido; Marta Ruiz-Ortega
Journal:  Biomed Res Int       Date:  2015-05-06       Impact factor: 3.411

9.  A mechanism of male germ cell apoptosis induced by bisphenol-A and nonylphenol involving ADAM17 and p38 MAPK activation.

Authors:  Paulina Urriola-Muñoz; Raúl Lagos-Cabré; Ricardo D Moreno
Journal:  PLoS One       Date:  2014-12-04       Impact factor: 3.240

Review 10.  A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems.

Authors:  Jiaxi Xu; Snigdha Mukerjee; Cristiane R A Silva-Alves; Alynne Carvalho-Galvão; Josiane C Cruz; Camille M Balarini; Valdir A Braga; Eric Lazartigues; Maria S França-Silva
Journal:  Front Physiol       Date:  2016-10-18       Impact factor: 4.566
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