Literature DB >> 24869947

The synthesis and structure of chiral enamine N-oxides.

I A O'Neil1, M McConville, K Zhou, C Brooke, C M Robertson, N G Berry.   

Abstract

Chiral enamine N-oxides have been synthesised by a diastereoselective intermolecular reverse-Cope cycloaddition reaction between chiral hydroxylamines and activated acetylenes. Their structures have been investigated by NMR, X-ray crystallography and computational methods.

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Year:  2014        PMID: 24869947     DOI: 10.1039/c3cc47928e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

1.  Bioorthogonal Retro-Cope Elimination Reaction of N,N-Dialkylhydroxylamines and Strained Alkynes.

Authors:  Dahye Kang; Justin Kim
Journal:  J Am Chem Soc       Date:  2021-04-08       Impact factor: 15.419

2.  Enamine N-Oxides: Synthesis and Application to Hypoxia-Responsive Prodrugs and Imaging Agents.

Authors:  Dahye Kang; Sheldon T Cheung; Andrew Wong-Rolle; Justin Kim
Journal:  ACS Cent Sci       Date:  2021-03-29       Impact factor: 14.553

3.  Bioorthogonal Hydroamination of Push-Pull-Activated Linear Alkynes.

Authors:  Dahye Kang; Sheldon T Cheung; Justin Kim
Journal:  Angew Chem Int Ed Engl       Date:  2021-06-24       Impact factor: 16.823

4.  Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols.

Authors:  Chen-Xi Ye; Yared Yohannes Melcamu; Heng-Hui Li; Jiang-Tao Cheng; Tian-Tian Zhang; Yuan-Ping Ruan; Xiao Zheng; Xin Lu; Pei-Qiang Huang
Journal:  Nat Commun       Date:  2018-01-29       Impact factor: 14.919

  4 in total

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