Literature DB >> 2486827

A very fast program for visualizing protein surfaces, channels and cavities.

R Voorintholt1, M T Kosters, G Vegter, G Vriend, W G Hol.   

Abstract

A method for visualizing molecular surfaces is described that uses a grid to store the distance to the nearest atom. Using on-the-fly three-dimensional (3D) contouring of a molecular graphics program such as FRODO, one can obtain a good impression of van der Waals surfaces and solvent-accessible surfaces. The main advantages of the method described here are its high speed and the fact that no recalculations need to be done to obtain the solvent-accessible surface visualized for a probe with another radius.

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Year:  1989        PMID: 2486827     DOI: 10.1016/0263-7855(89)80010-4

Source DB:  PubMed          Journal:  J Mol Graph        ISSN: 0263-7855


  19 in total

1.  Fast prediction and visualization of protein binding pockets with PASS.

Authors:  G P Brady; P F Stouten
Journal:  J Comput Aided Mol Des       Date:  2000-05       Impact factor: 3.686

2.  Are proteins well-packed?

Authors:  J Liang; K A Dill
Journal:  Biophys J       Date:  2001-08       Impact factor: 4.033

3.  Cavity search: an algorithm for the isolation and display of cavity-like binding regions.

Authors:  C M Ho; G R Marshall
Journal:  J Comput Aided Mol Des       Date:  1990-12       Impact factor: 3.686

4.  Determination of the interfacial water content in protein-protein complexes from free energy simulations.

Authors:  Peter Monecke; Thorsten Borosch; Jürgen Brickmann; Stefan M Kast
Journal:  Biophys J       Date:  2005-11-11       Impact factor: 4.033

5.  Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design.

Authors:  J Liang; H Edelsbrunner; C Woodward
Journal:  Protein Sci       Date:  1998-09       Impact factor: 6.725

6.  G protein-coupled receptors of class A harness the energy of membrane potential to increase their sensitivity and selectivity.

Authors:  Daria N Shalaeva; Dmitry A Cherepanov; Michael Y Galperin; Gert Vriend; Armen Y Mulkidjanian
Journal:  Biochim Biophys Acta Biomembr       Date:  2019-08-23       Impact factor: 3.747

7.  Geometric Detection Algorithms for Cavities on Protein Surfaces in Molecular Graphics: A Survey.

Authors:  Tiago Simões; Daniel Lopes; Sérgio Dias; Francisco Fernandes; João Pereira; Joaquim Jorge; Chandrajit Bajaj; Abel Gomes
Journal:  Comput Graph Forum       Date:  2017-06-01       Impact factor: 2.078

Review 8.  Prediction and analysis of structure, stability and unfolding of thermolysin-like proteases.

Authors:  G Vriend; V Eijsink
Journal:  J Comput Aided Mol Des       Date:  1993-08       Impact factor: 3.686

9.  Structural investigations and modeling of cavities in clathrates.

Authors:  L Pang; E A Lucken; J Weber; G Bernardinelli
Journal:  J Comput Aided Mol Des       Date:  1991-08       Impact factor: 3.686

10.  A novel and efficient tool for locating and characterizing protein cavities and binding sites.

Authors:  Ashutosh Tripathi; Glen E Kellogg
Journal:  Proteins       Date:  2010-03
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