Literature DB >> 24868100

Patterns of storage, use, and disposal of opioids among cancer outpatients.

Akhila Reddy1, Maxine de la Cruz2, Eden Mae Rodriguez2, Jessica Thames2, Jimin Wu2, Gary Chisholm2, Diane Liu2, Susan Frisbee-Hume2, Sriram Yennurajalingam2, David Hui2, Hilda Cantu2, Alejandra Marin2, Vicki Gayle2, Nancy Shinn2, Angela Xu2, Janet Williams2, Eduardo Bruera2.   

Abstract

PURPOSE: Improper storage, use, and disposal of prescribed opioids can lead to diversion or accidental poisoning. Our objective was to determine the patterns of storage, utilization, and disposal of opioids among cancer outpatients. PATIENTS AND METHODS: We surveyed 300 adult cancer outpatients receiving opioids in our supportive care center and collected information regarding opioid use, storage, and disposal, along with scores on the CAGE (cut down, annoyed, guilty, eye-opener) alcoholism screening questionnaire. Unsafe use was defined as sharing or losing opioids; unsafe storage was defined as storing opioids in plain sight.
RESULTS: The median age was 57 years. CAGE was positive in 58 of 300 patients (19%), and 26 (9%) had a history of illicit drug use. Fifty-six (19%) stored opioids in plain sight, 208 (69%) kept opioids hidden but unlocked, and only 28 (9%) locked their opioids. CAGE-positive patients (p = .007) and those with a history of illicit drug use (p = .0002) or smoking (p = .03) were more likely to lock their opioids. Seventy-eight (26%) reported unsafe use by sharing (9%) or losing (17%) their opioids. Patients who were never married or single (odds ratio: 2.92; 95% confidence interval: 1.48-5.77; p = .006), were CAGE positive (40% vs. 21%; p = .003), or had a history of illicit drug use (42% vs. 23%; p = .031) were more likely to use opioids unsafely. Overall, 223 of 300 patients (74%) were unaware of proper opioid disposal methods, and 138 (46%) had unused opioids at home.
CONCLUSION: A large proportion of cancer patients improperly and unsafely use, store, and dispose of opioids, highlighting the need for establishment of easily accessed patient education and drug take-back programs. ©AlphaMed Press.

Entities:  

Keywords:  Cancer; Drug storage; Medical waste disposal; Opioid analgesics; Palliative care; Prescription drug diversion

Mesh:

Substances:

Year:  2014        PMID: 24868100      PMCID: PMC4077453          DOI: 10.1634/theoncologist.2014-0071

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  31 in total

1.  JCAHO pain management standards are unveiled. Joint Commission on Accreditation of Healthcare Organizations.

Authors:  D M Phillips
Journal:  JAMA       Date:  2000-07-26       Impact factor: 56.272

2.  Ensuring effective pain treatment: a national and global perspective.

Authors:  Allyn L Taylor; Lawrence O Gostin; Katrina A Pagonis
Journal:  JAMA       Date:  2008-01-02       Impact factor: 56.272

Review 3.  Current regulations and modest proposals regarding disposal of unused opioids and other controlled substances.

Authors:  Marvin E Herring; Shinil K Shah; Shiwan K Shah; Adarsh K Gupta
Journal:  J Am Osteopath Assoc       Date:  2008-07

Review 4.  American pain society recommendations for improving the quality of acute and cancer pain management: American Pain Society Quality of Care Task Force.

Authors:  Debra B Gordon; June L Dahl; Christine Miaskowski; Bill McCarberg; Knox H Todd; Judith A Paice; Arthur G Lipman; Marilyn Bookbinder; Steve H Sanders; Dennis C Turk; Daniel B Carr
Journal:  Arch Intern Med       Date:  2005-07-25

5.  Pain as a human right: the 2004 Global Day Against Pain.

Authors:  Arthur G Lipman
Journal:  J Pain Palliat Care Pharmacother       Date:  2005

6.  Management of cancer pain.

Authors:  R K Portenoy; P Lesage
Journal:  Lancet       Date:  1999-05-15       Impact factor: 79.321

7.  Patient practices and beliefs concerning disposal of medications.

Authors:  Dean A Seehusen; John Edwards
Journal:  J Am Board Fam Med       Date:  2006 Nov-Dec       Impact factor: 2.657

8.  Screening for alcohol abuse using the CAGE questionnaire.

Authors:  B Bush; S Shaw; P Cleary; T L Delbanco; M D Aronson
Journal:  Am J Med       Date:  1987-02       Impact factor: 4.965

9.  Home medication cabinets and self-medication: a source of potential health threats?

Authors:  Leen De Bolle; Els Mehuys; Els Adriaens; Jean-Paul Remon; Luc Van Bortel; Thierry Christiaens
Journal:  Ann Pharmacother       Date:  2008-03-25       Impact factor: 3.154

10.  Safe storage of methadone takeaway doses - a survey of patient practice.

Authors:  Adam R Winstock; Toby Lea
Journal:  Aust N Z J Public Health       Date:  2007-12       Impact factor: 2.939

View more
  26 in total

Review 1.  Best Practices in the Management of Nonmedical Opioid Use in Patients with Cancer-Related Pain.

Authors:  Esad Ulker; Egidio Del Fabbro
Journal:  Oncologist       Date:  2019-12-24

2.  Prescription Disposal Practices: A 2-Year Ecological Study of Drug Drop Box Donations in Appalachia.

Authors:  Jeffrey Gray; Nicholas Hagemeier; Billy Brooks; Arsham Alamian
Journal:  Am J Public Health       Date:  2015-07-16       Impact factor: 9.308

3.  Effect of an Activated Charcoal Bag on Disposal of Unused Opioids After an Outpatient Surgical Procedure: A Randomized Clinical Trial.

Authors:  Chad M Brummett; Rena Steiger; Michael Englesbe; Caitlin Khalsa; Jennie J DeBlanc; Lindsay R Denton; Jennifer Waljee
Journal:  JAMA Surg       Date:  2019-06-01       Impact factor: 14.766

Review 4.  Opioid Prescribing in an Opioid Crisis: What Basic Skills Should an Oncologist Have Regarding Opioid Therapy?

Authors:  Joseph Arthur; Akhila Reddy
Journal:  Curr Treat Options Oncol       Date:  2019-04-01

5.  The Impact of an Educational Program on Patient Practices for Safe Use, Storage, and Disposal of Opioids at a Comprehensive Cancer Center.

Authors:  Maxine de la Cruz; Akhila Reddy; Vishidha Balankari; Margeaux Epner; Susan Frisbee-Hume; Jimin Wu; Diane Liu; Sriram Yennuraialingam; Hilda Cantu; Janet Williams; Eduardo Bruera
Journal:  Oncologist       Date:  2016-10-14

6.  Patterns of Opioid Prescription, Use, and Costs Among Patients With Advanced Cancer and Inpatient Palliative Care Between 2008 and 2014.

Authors:  Sriram Yennurajalingam; Zhanni Lu; Suresh K Reddy; EdenMae C Rodriguez; Kristy Nguyen; Marie J Waletich-Flemming; Kyu-Hyoung Lim; Aksha Memon; Nhu-Nhu Nguyen; Kristy W Rofheart; Guoqin Wang; Srikanth Reddy Barla; Jimin Wu; Janet L Williams; Eduardo Bruera
Journal:  J Oncol Pract       Date:  2018-11-29       Impact factor: 3.840

7.  A statewide evaluation of seven strategies to reduce opioid overdose in North Carolina.

Authors:  Apostolos A Alexandridis; Agnieszka McCort; Christopher L Ringwalt; Nidhi Sachdeva; Catherine Sanford; Stephen W Marshall; Karin Mack; Nabarun Dasgupta
Journal:  Inj Prev       Date:  2017-08-23       Impact factor: 2.399

8.  Overall Survival among Cancer Patients Undergoing Opioid Rotation to Methadone Compared to Other Opioids.

Authors:  Akhila Reddy; Ulrich S Schuler; Maxine de la Cruz; Sriram Yennurajalingam; Jimin Wu; Diane Liu; Eduardo Bruera
Journal:  J Palliat Med       Date:  2016-12-20       Impact factor: 2.947

Review 9.  Safe Opioid Use, Storage, and Disposal Strategies in Cancer Pain Management.

Authors:  Akhila Reddy; Maxine de la Cruz
Journal:  Oncologist       Date:  2019-05-16

10.  Adolescents' awareness about prescription opioid misuse and preferences for educational interventions.

Authors:  Olufunmilola Abraham; Lisa Szela; Derek Norton; Haley Stafford; Margaret Hoernke; Randall Brown
Journal:  J Am Pharm Assoc (2003)       Date:  2020-08-29
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.