Literature DB >> 2486523

[Experimental cutaneous leishmaniasis: I--on the susceptibility of the primate Cebus apella (Cebidae) to the infection caused by Leishmania (Viannia) lainsoni Silveira, Shaw and Ishikawa, 1987].

F T Silveira, R Lainson, J J Shaw, L M Garcez, A A Souza, R R Braga, E A Ishikawa.   

Abstract

The susceptibility of the monkey Cebus apella (Cebidae) to experimental infection by Leishmania (Viannia) lainsoni has been investigated. For this purpose, five young monkeys, 2 males and 3 females, were intradermally, inoculated, in eight different places along the dorsal surface of the tail with 3 x 10(6) promastigotes of the parasite (MHOM/BR/81/M6426, Benevides, Pará), from stationary phase culture in Difco B45 medium. After inoculations, infection in the monkeys was indicated by the presence of amastigotes in the skin lesions produced in these animals at the points of inoculation, confirming the susceptibility of the monkey Cebus apella to experimental infection by Leishmania lainsoni, with an infection period of four months. This represents a suitable period for testing antileishmanial drugs or studying the pathogenesis of the disease caused by this parasite.

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Year:  1989        PMID: 2486523     DOI: 10.1590/s0037-86821989000300003

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  2 in total

1.  Leishmania infection and blood food sources of phlebotomines in an area of Brazil endemic for visceral and tegumentary leishmaniasis.

Authors:  Antônia Suely Guimarães-E-Silva; Soraia de Oliveira Silva; Rosa Cristina Ribeiro da Silva; Valéria Cristina Soares Pinheiro; José Manuel Macário Rebêlo; Maria Norma Melo
Journal:  PLoS One       Date:  2017-08-24       Impact factor: 3.240

2.  Dynamic of the cellular immune response at the dermal site of Leishmania (L.) amazonensis and Leishmania (V.) braziliensis infection in Sapajus apella primate.

Authors:  Márcia Dalastra Laurenti; Luiz Felipe Domingues Passero; Thaise Yumie Tomokane; Fernanda de Camargo Francesquini; Mussya Cisotto Rocha; Claudia Maria de Castro Gomes; Carlos Eduardo Pereira Corbett; Fernando Tobias Silveira
Journal:  Biomed Res Int       Date:  2014-08-28       Impact factor: 3.411

  2 in total

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