| Literature DB >> 24864040 |
C Tony Liu1, John W Tomsho2, Stephen J Benkovic3.
Abstract
Benzoxaboroles have garnered much attention in recent years due to their diverse applications in bio-sensing technology, material science, and therapeutic intervention. Part of the reason arises from the benzoxaboroles' unique chemical properties, especially in comparison to their acyclic boronic acid counterparts. Furthermore, the low bio-toxicity combined with the high target specificity associated with benzoxaboroles make them very attractive as therapeutic agents. Herein, we provide an updated summary on the current knowledge of the fundamental chemical reactivity of benzoxaboroles, followed by highlighting their major applications reported to date.Entities:
Keywords: Benzoboroxole; Benzoxaborole; Boronic acid; Oxaborole; Sulfenic acid
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Year: 2014 PMID: 24864040 DOI: 10.1016/j.bmc.2014.04.065
Source DB: PubMed Journal: Bioorg Med Chem ISSN: 0968-0896 Impact factor: 3.641