C Mottolese1, A Szathmari2, A C Ricci-Franchi2, P Gallo2, P A Beuriat2, G Capone2. 1. Service of Pediatric Neurosurgery, Neurological and Neurosurgical Hospital "P. Wertheimer", 59, boulevard Pinel, 69677 Bron, France. Electronic address: carmine.mottolese@chu-lyon.fr. 2. Service of Pediatric Neurosurgery, Neurological and Neurosurgical Hospital "P. Wertheimer", 59, boulevard Pinel, 69677 Bron, France.
Abstract
UNLABELLED: The infratentorial supracerebellar approach is most widely used for pineal tumors. We report our own experience and technical considerations using this approach. MATERIAL: From 1982 to 2010, we operated on 232 patients with pineal region tumors. Of these, 201 patients were operated on using a suboccipital transtentorial approach while 31 patients were operated on using a supracerebellar infratentorial approach. The median age of the patients ranged between 8 months and 74 years. There were 19 children and 12 adults. All patients presented with elevated intracranial pressure. There were 6 pinealocytomas, 3 papillary tumors, 7 germinomas, 2 benign teratomas, 4 pineal cysts and 9 gliomas. Adjuvant post-surgical therapy consisted of chemo-radiotherapy in 4 patients, 2 with germinomas and 2 with a grade II/III gliomas. Radiotherapy was performed in the other twelve patients (5 germinomas and 7 gliomas). RESULTS AND COMPLICATIONS: All patients are still alive at a median follow-up of eight years. Twelve of the 19 children are attending normal school classes for their age, 5 are attending classes for special needs children and 2 are not yet of school age at the last follow-up. Seven of the 12 adults are working normally, three are working part-time at the same job and two have retired but are able to lead a normal life. Postoperative complications included symptomatic diffuse cerebellar edema (one patient) completely resolved with a mild residual cerebellar syndrome; double vision secondary to IV nerve palsy (one patient); transitory Parinaud's syndrome (2 patients) and cerebellar gait (2 patients) nearly completely recovered at respectively six and twelve months. CONCLUSION: The supracerebellar infratentorial approach seems to be a safe and effective choice in the treatment of pineal region tumors. In our experience, it permits complete tumor resections with acceptable morbidity and all neurosurgeons should master this approach in order to adapt their surgical choice according to size, extent and the relationship of the lesion with the surrounding anatomical structures.
UNLABELLED: The infratentorial supracerebellar approach is most widely used for pineal tumors. We report our own experience and technical considerations using this approach. MATERIAL: From 1982 to 2010, we operated on 232 patients with pineal region tumors. Of these, 201 patients were operated on using a suboccipital transtentorial approach while 31 patients were operated on using a supracerebellar infratentorial approach. The median age of the patients ranged between 8 months and 74 years. There were 19 children and 12 adults. All patients presented with elevated intracranial pressure. There were 6 pinealocytomas, 3 papillary tumors, 7 germinomas, 2 benign teratomas, 4 pineal cysts and 9 gliomas. Adjuvant post-surgical therapy consisted of chemo-radiotherapy in 4 patients, 2 with germinomas and 2 with a grade II/III gliomas. Radiotherapy was performed in the other twelve patients (5 germinomas and 7 gliomas). RESULTS AND COMPLICATIONS: All patients are still alive at a median follow-up of eight years. Twelve of the 19 children are attending normal school classes for their age, 5 are attending classes for special needs children and 2 are not yet of school age at the last follow-up. Seven of the 12 adults are working normally, three are working part-time at the same job and two have retired but are able to lead a normal life. Postoperative complications included symptomatic diffuse cerebellar edema (one patient) completely resolved with a mild residual cerebellar syndrome; double vision secondary to IV nerve palsy (one patient); transitory Parinaud's syndrome (2 patients) and cerebellar gait (2 patients) nearly completely recovered at respectively six and twelve months. CONCLUSION: The supracerebellar infratentorial approach seems to be a safe and effective choice in the treatment of pineal region tumors. In our experience, it permits complete tumor resections with acceptable morbidity and all neurosurgeons should master this approach in order to adapt their surgical choice according to size, extent and the relationship of the lesion with the surrounding anatomical structures.
Keywords:
Abord supra-cérébelleux infratentoriel; Microchirurgie; Microsurgery; Pineal region tumor; Pineal tumor; Supracerebellar infratentorial approach; Tumeur de la pinéale; Tumeur de la région pinéale
Authors: Matthew J Shepard; Ali S Haider; Sujit S Prabhu; Raymond Sawaya; Franco DeMonte; Ian E McCutcheon; Jeffrey S Weinberg; Sherise D Ferguson; Dima Suki; Gregory N Fuller; Frederick F Lang Journal: J Neurooncol Date: 2022-01-27 Impact factor: 4.130
Authors: Ehab Shabo; Thomas Czech; James C Nicholson; Conor Mallucci; Carmine Mottolese; Gianluca Piatelli; Didier Frappaz; Matthew Jonathan Murray; Cecile Faure-Conter; Maria Luisa Garrè; Sevgi Sarikaya-Seiwert; Leonie Weinhold; Hannes Haberl; Gabriele Calaminus Journal: Cancers (Basel) Date: 2022-07-21 Impact factor: 6.575