| Literature DB >> 24862497 |
Xiang-Jing Wang1, Ji Zhang, Ping-Ting Qian, Ji-Dong Wang, Chong-Xi Liu, Wen-Sheng Xiang.
Abstract
Three new cyclopentenone derivatives (1-3) were isolated from the rare actinomycete Actinoalloteichus nanshanensis NEAU 119. Their structures were elucidated by extensive spectroscopic analysis. Compound 1 showed moderate cytotoxic activity against human lung adenocarcinoma cell line A549, human leukemia cell line K562, and human renal carcinoma cell line ACHN with an IC50 of 14.67, 11.87, and 23.36 μg ml(-1), respectively.Entities:
Keywords: Actinoalloteichus nanshanensis NEAU 119; cyclopentenone; cytotoxic activity
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Year: 2014 PMID: 24862497 DOI: 10.1080/10286020.2014.921909
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN: 1028-6020 Impact factor: 1.569