OBJECTIVES: To develop effective intervention programmes to control Clonorchis sinensis infection, three interventions were evaluated in a clonorchiasis-endemic area of Korea. METHODS: Four thousand two hundred and sixty-seven voluntary participants in Sancheong county were tested at baseline and two follow-up surveys after 1 and 3 years. Faecal samples were examined for C. sinensis eggs using the Kato-Katz method. Participants were divided into three intervention groups by areas and year recruited: national prevention programme only (mass health campaign and praziquantel treatment) for Group A; health education for community leaders added for Group B; and individual health education added for Group C. RESULTS: The prevalence of C. sinensis infection fell substantially in all three intervention groups between baseline and 3-year follow-up: from 31.1% to 14.9% in Group A, from 29.6% to 6.8% in Group B and from 21.9% to 8.6% in Group C. The control effectiveness was highest in Group B with 76.8%. The new infection rate was 16.3%, 12.8% and 7.6% in Group A, B and C, respectively. The reinfection rate was lower in Group B (3.8%) than Group C (12.2%). CONCLUSIONS: To control C. sinensis infection in endemic areas of Korea, health education for community leaders or individuals on prevention of C. sinensis infection should be added to national control programmes.
OBJECTIVES: To develop effective intervention programmes to control Clonorchis sinensisinfection, three interventions were evaluated in a clonorchiasis-endemic area of Korea. METHODS: Four thousand two hundred and sixty-seven voluntary participants in Sancheong county were tested at baseline and two follow-up surveys after 1 and 3 years. Faecal samples were examined for C. sinensis eggs using the Kato-Katz method. Participants were divided into three intervention groups by areas and year recruited: national prevention programme only (mass health campaign and praziquantel treatment) for Group A; health education for community leaders added for Group B; and individual health education added for Group C. RESULTS: The prevalence of C. sinensisinfection fell substantially in all three intervention groups between baseline and 3-year follow-up: from 31.1% to 14.9% in Group A, from 29.6% to 6.8% in Group B and from 21.9% to 8.6% in Group C. The control effectiveness was highest in Group B with 76.8%. The new infection rate was 16.3%, 12.8% and 7.6% in Group A, B and C, respectively. The reinfection rate was lower in Group B (3.8%) than Group C (12.2%). CONCLUSIONS: To control C. sinensisinfection in endemic areas of Korea, health education for community leaders or individuals on prevention of C. sinensisinfection should be added to national control programmes.
Keywords:
Clonorchis sinensis; Endemicidad; Praziquantel; control effectiveness; contrôle de l'efficacité; educación sanitaria; efectividad del control; endemicity; endémicité; field intervention; health education; intervención de campo; intervention sur le terrain; praziquantel; éducation à la santé
Authors: Seung Ho Choi; Changhyun Lee; Jong In Yang; Min-Sun Kwak; Goh Eun Chung; Hae Yeon Kang; Su Jin Chung; Jeong Yoon Yim; Joo Sung Kim Journal: Am J Trop Med Hyg Date: 2017-07-27 Impact factor: 2.345