| Literature DB >> 24856295 |
Claude Libert1, Lien Dejager2.
Abstract
Recent papers from Mahata et al. and Bereshchenko et al. reveal how steroids steer immune responses by tipping T helper (Th) subset balances and activities. Pregnenolone produced by Th2 cells mediates immunosuppressive responses, and glucocorticoids stimulate regulatory T cell development via the induction of GILZ expression.Entities:
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Year: 2014 PMID: 24856295 DOI: 10.1016/j.celrep.2014.04.041
Source DB: PubMed Journal: Cell Rep Impact factor: 9.423