| Literature DB >> 24856136 |
Libera Berghella1, Pier Lorenzo Puri2.
Abstract
Previous work linked nitric oxide (NO) signaling to histone deacetelyases (HDACs) in the control of tissue homeostasis and suggested that deregulation of this signaling contributes to human diseases. In the previous issue of Chemistry & Biology, Kong and colleagues showed that coordinated NO signaling and histone acetylation are required for proper cranial neural crest development and craniofacial morphogenesis and suggested that alterations of NO/acetylation network can contribute to the pathogenesis of craniofacial malformations.Entities:
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Year: 2014 PMID: 24856136 PMCID: PMC4114503 DOI: 10.1016/j.chembiol.2014.05.002
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521