| Literature DB >> 24855937 |
Sophie M Steculorum1, Jens C Brüning2.
Abstract
Riera et al. identify a neuroendocrine circuit that controls longevity and the age-dependent onset of metabolic decline via the pain-transducing channel TRPV1. Thus, pharmacological inhibition of TRPV1 may provide a new approach to treat not only metabolic disorders but also a broader range of age-related pathologies.Entities:
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Year: 2014 PMID: 24855937 DOI: 10.1016/j.cell.2014.05.013
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582