Literature DB >> 24853896

Physiology helps GWAS take a step closer to mechanism.

Timothy M Frayling1, Andrew T Hattersley2.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 24853896     DOI: 10.2337/db14-0130

Source DB:  PubMed          Journal:  Diabetes        ISSN: 0012-1797            Impact factor:   9.461


× No keyword cloud information.
  5 in total

1.  Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association With Insulin Clearance.

Authors:  Mark O Goodarzi; Nicholette D Palmer; Jinrui Cui; Xiuqing Guo; Yii-Der I Chen; Kent D Taylor; Leslie J Raffel; Lynne E Wagenknecht; Thomas A Buchanan; Willa A Hsueh; Jerome I Rotter
Journal:  J Clin Endocrinol Metab       Date:  2020-04-01       Impact factor: 5.958

2.  Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion.

Authors:  Hanieh Yaghootkar; Alena Stancáková; Rachel M Freathy; Jagadish Vangipurapu; Michael N Weedon; Weijia Xie; Andrew R Wood; Ele Ferrannini; Andrea Mari; Susan M Ring; Debbie A Lawlor; George Davey Smith; Torben Jørgensen; Torben Hansen; Oluf Pedersen; Valgerdur Steinthorsdottir; Daniel F Guðbjartsson; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Kari Stefansson; Andrew T Hattersley; Mark Walker; Andrew D Morris; Mark I McCarthy; Colin N A Palmer; Markku Laakso; Timothy M Frayling
Journal:  Diabetes       Date:  2015-01-20       Impact factor: 9.461

Review 3.  Using Drosophila to discover mechanisms underlying type 2 diabetes.

Authors:  Ronald W Alfa; Seung K Kim
Journal:  Dis Model Mech       Date:  2016-04       Impact factor: 5.758

4.  The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.

Authors:  Jose M Mellado-Gil; Esther Fuente-Martín; Petra I Lorenzo; Nadia Cobo-Vuilleumier; Livia López-Noriega; Alejandro Martín-Montalvo; Irene de Gracia Herrera Gómez; Maria Ceballos-Chávez; Laura Gómez-Jaramillo; Antonio Campos-Caro; Silvana Y Romero-Zerbo; Júlia Rodríguez-Comas; Joan-Marc Servitja; Gemma Rojo-Martinez; Abdelkrim Hmadcha; Bernat Soria; Marco Bugliani; Piero Marchetti; Francisco J Bérmudez-Silva; Jose C Reyes; Manuel Aguilar-Diosdado; Benoit R Gauthier
Journal:  Cell Death Dis       Date:  2018-02-15       Impact factor: 8.469

5.  Influence of Feature Encoding and Choice of Classifier on Disease Risk Prediction in Genome-Wide Association Studies.

Authors:  Florian Mittag; Michael Römer; Andreas Zell
Journal:  PLoS One       Date:  2015-08-18       Impact factor: 3.240

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.