| Literature DB >> 24853662 |
Cristina Marculescu1, Hanno Kossen, Rachel E Morgan, Patrick Mayer, Sally A Fletcher, Berend Tolner, Kerry A Chester, Lyn H Jones, James R Baker.
Abstract
Tuning the properties of maleimide reagents holds significant promise in expanding the toolbox of available methods for bioconjugation. Herein we describe aryloxymaleimides which represent 'next generation maleimides' of attenuated reactivity, and demonstrate their ability to enable new methods for protein modification at disulfide bonds.Entities:
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Year: 2014 PMID: 24853662 DOI: 10.1039/c4cc02107j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222