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Literature DB >> 24853539

Fecal microbiota transplantation in children with recurrent Clostridium difficile infection.

Anne Pierog¹, Ali Mencin, Norelle Rizkalla Reilly.

Abstract

Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.

Entities: Disease Species

Mesh：

Year: 2014 PMID： 24853539 DOI： 10.1097/INF.0000000000000419

Source DB: PubMed Journal: Pediatr Infect Dis J ISSN： 0891-3668 Impact factor: 2.129

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Cited

13 in total

Review 1. Recent Issues in Pediatric Clostridium difficile Infection.

Authors: Jason A Clayton; Philip Toltzis
Journal: Curr Infect Dis Rep Date: 2017-11-07 Impact factor: 3.725

2. Transmission and clearance of potential procarcinogenic bacteria during fecal microbiota transplantation for recurrent Clostridioides difficile.

Authors: Julia L Drewes; Alina Corona; Uriel Sanchez; Yunfan Fan; Suchitra K Hourigan; Melissa Weidner; Sarah D Sidhu; Patricia J Simner; Hao Wang; Winston Timp; Maria Oliva-Hemker; Cynthia L Sears
Journal: JCI Insight Date: 2019-10-03

Review 3. Fecal microbiota transplantation in children: a brief review.

Authors: Suchitra K Hourigan; Maria Oliva-Hemker
Journal: Pediatr Res Date: 2016-03-16 Impact factor: 3.756

Review 4. Control of Clostridium difficile Infection by Defined Microbial Communities.

Authors: James Collins; Jennifer M Auchtung
Journal: Microbiol Spectr Date: 2017-09

Review 5. Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook.

Authors: Colleen R Kelly; Stacy Kahn; Purna Kashyap; Loren Laine; David Rubin; Ashish Atreja; Thomas Moore; Gary Wu
Journal: Gastroenterology Date: 2015-05-15 Impact factor: 22.682

6. Novel microbiome-based therapeutics for chronic rhinosinusitis.

Authors: E K Cope; S V Lynch
Journal: Curr Allergy Asthma Rep Date: 2015-03 Impact factor: 4.806

Review 7. Microbial therapeutic interventions.

Authors: Nicole G Grady; Elaine O Petrof; Erika C Claud
Journal: Semin Fetal Neonatal Med Date: 2016-04-25 Impact factor: 3.926

Review 8. Fecal Microbiota Therapy for Clostridium difficile Infection: A Health Technology Assessment.

Authors:
Journal: Ont Health Technol Assess Ser Date: 2016-07-01

Review 9. The Significance of the Enteric Microbiome on the Development of Childhood Disease: A Review of Prebiotic and Probiotic Therapies in Disorders of Childhood.

Authors: John Slattery; Derrick F MacFabe; Richard E Frye
Journal: Clin Med Insights Pediatr Date: 2016-10-09

Review 10. Systematic Review: Adverse Events of Fecal Microbiota Transplantation.

Authors: Sinan Wang; Mengque Xu; Weiqiang Wang; Xiaocang Cao; Meiyu Piao; Samiullah Khan; Fang Yan; Hailong Cao; Bangmao Wang
Journal: PLoS One Date: 2016-08-16 Impact factor: 3.240