Literature DB >> 24850875

United Kingdom survey of current management of juvenile localized scleroderma.

Daniel P Hawley1, Clare E Pain2, Eileen M Baildam2, Ruth Murphy2, Aileen E M Taylor2, Helen E Foster3.   

Abstract

OBJECTIVES: Juvenile localized scleroderma (JLS) is a rare condition that is often difficult to assess and for which a variety of monitoring tools have been described. We aimed to describe how monitoring tools are used and perceived by clinicians in the UK, to ascertain treatments used for JLS and to provide a description of transition arrangements to adult care.
METHODS: An e-survey of UK paediatric rheumatologists and dermatologists managing children and young people (CYP) with JLS was distributed using the national organisations representing these clinician groups. We asked respondents for their views and experience using 15 JLS monitoring tools, about transition services and about treatments used.
RESULTS: Thirty-five dermatologists and 13 paediatric rheumatologists responded. Paediatric rheumatologists managed more CYP with JLS than dermatologists (median 16-20 and 3, respectively). Transition arrangements were reported by 43% of dermatologists and 91% of paediatric rheumatologists. Medical photography was the most frequently regularly used monitoring tool (73% respondents). The modified Rodnan skin score was the skin score used most commonly: 33% of paediatric rheumatologists and 3% of dermatologists reported using this tool frequently. Topical treatments and ultraviolet light were used by 49-80% of dermatologists and 0-8% paediatric rheumatologists. Biologic drugs and CYC were used by 0-3% of dermatologists and 31-46% of paediatric rheumatologists.
CONCLUSION: How monitoring tools are accessed, used and perceived by paediatric rheumatologists and dermatologists in the UK varies between and within clinician groups, as do treatment prescribing patterns and transition arrangements. These differences will impact on the feasibility of conducting multicentre clinical trials and on standardising clinical care.
© The Author 2014. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  access to care; laser Doppler; localized scleroderma; magnetic resonance imaging; paediatric; photography; skin; skin score; thermography; ultrasound

Mesh:

Substances:

Year:  2014        PMID: 24850875     DOI: 10.1093/rheumatology/keu212

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN: 1462-0324            Impact factor:   7.580


  11 in total

Review 1.  A Practical Approach to Juvenile Dermatomyositis and Juvenile Scleroderma.

Authors:  Liza J McCann; Clare E Pain
Journal:  Indian J Pediatr       Date:  2016-02       Impact factor: 1.967

2.  Comparing paediatric- and adult-onset linear morphoea in a large tertiary-referral scleroderma centre.

Authors:  Amanda M Saracino; Christina George; Svetlana I Nihtyanova; Christopher P Denton
Journal:  J Scleroderma Relat Disord       Date:  2020-06-12

Review 3.  Development of minimum standards of care for juvenile localized scleroderma.

Authors:  Tamás Constantin; Ivan Foeldvari; Clare E Pain; Annamária Pálinkás; Peter Höger; Monika Moll; Dana Nemkova; Lisa Weibel; Melinda Laczkovszki; Philip Clements; Kathryn S Torok
Journal:  Eur J Pediatr       Date:  2018-05-04       Impact factor: 3.183

Review 4.  Overview of Juvenile localized scleroderma and its management.

Authors:  Suzanne C Li; Rong-Jun Zheng
Journal:  World J Pediatr       Date:  2019-11-30       Impact factor: 2.764

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Review 6.  Improving musculoskeletal health for children and young people - A 'call to action'.

Authors:  Helen E Foster; Christiaan Scott; Carl J Tiderius; Matthew B Dobbs
Journal:  Best Pract Res Clin Rheumatol       Date:  2020-07-26       Impact factor: 4.098

7.  Multi-centre national audit of juvenile localised scleroderma: describing current UK practice in disease assessment and management.

Authors:  Hanna Lythgoe; Beverley Almeida; Joshua Bennett; Chandrika Bhat; Amarpal Bilkhu; Mary Brennan; Samundeeswari Deepak; Pamela Dawson; Despina Eleftheriou; Kathryn Harrison; Daniel Hawley; Eleanor Heaf; Valentina Leone; Ema Long; Sarah Maltby; Flora McErlane; Nadia Rafiq; Athimalaipet V Ramanan; Phil Riley; Satyapal Rangaraj; Giulia Varnier; Nick Wilkinson; Clare E Pain
Journal:  Pediatr Rheumatol Online J       Date:  2018-12-18       Impact factor: 3.054

Review 8.  Phototherapy in Scleroderma.

Authors:  John Hassani; Steven R Feldman
Journal:  Dermatol Ther (Heidelb)       Date:  2016-08-12

9.  Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression.

Authors:  Ming Keat Sng; Jeremy Soon Kiat Chan; Ziqiang Teo; Terri Phua; Eddie Han Pin Tan; Jonathan Wei Kiat Wee; Nikki Jun Ning Koh; Chek Kun Tan; Jia Peng Chen; Mintu Pal; Benny Meng Kiat Tong; Ya Lin Tnay; Xuan Rui Ng; Pengcheng Zhu; Shunsuke Chiba; Xiaomeng Wang; Walter Wahli; Nguan Soon Tan
Journal:  Cell Discov       Date:  2018-04-03       Impact factor: 10.849

10.  Magnetic Resonance Imaging Evaluation in Patients with Linear Morphea Treated with Methotrexate and High-Dose Corticosteroid.

Authors:  Mohammad Shahidi-Dadras; Fahimeh Abdollahimajd; Razieh Jahangard; Ali Javinani; Amir Ashraf-Ganjouei; Parviz Toossi
Journal:  Dermatol Res Pract       Date:  2018-07-02
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