| Literature DB >> 24849830 |
Yu-Fan Cheng1, Hsin-You Ou, Chun-Yen Yu, Leo Leung-Chit Tsang, Tung-Liang Huang, Tai-Yi Chen, Allan Concejero, Chih-Chi Wang, Shih-Ho Wang, Tsan-Shiun Lin, Yueh-Wei Liu, Chin-Hsiang Yang, Chee-Chien Yong, King-Wah Chiu, Bruno Jawan, Hock-Liew Eng, Chao-Long Chen.
Abstract
Portal vein (PV) complications after living donor liver transplant (LDLT) have been a major concern in pediatric liver transplantation. The incidence of PV complications is more in pediatric (0%-33%) than in adult recipients. Early diagnosis and treatment of PV complications may ensure optimal graft function and good recipient survival. Small preoperation PV size (<4 mm) and slow portal flow (<10 cm/s) combined with lower hepatic artery resistance index (<0.65) are strong warning signs that may predict the development of post LDLT PV complications. Portal vein angioplasty/stenting is conventionally performed through the percutaneous transhepatic approach; however, this can also be performed through transjugular, trans-splenic, and intraoperative approaches. Depending on the situation, using optimal method is the key point to minimize complication (5%) and gain high success rate (80%). PV occlusion of greater than 1 year with cavernous transformation seems to be a factor causing technical failure. Good patency rate (100%) with self-expandable metallic stents was noted in long-term follow-up. In conclusion, PV stent placement is an effective, long-term treatment modality to manage PV complications after pediatric LDLT. Early diagnosis and treatment are essential to maximize the use of stent placement and achieve good success rates.Entities:
Mesh:
Year: 2014 PMID: 24849830 DOI: 10.1097/01.tp.0000446272.05687.ce
Source DB: PubMed Journal: Transplantation ISSN: 0041-1337 Impact factor: 4.939