Literature DB >> 24849830

Section 8. Management of portal venous complications in pediatric living donor liver transplantation.

Yu-Fan Cheng1, Hsin-You Ou, Chun-Yen Yu, Leo Leung-Chit Tsang, Tung-Liang Huang, Tai-Yi Chen, Allan Concejero, Chih-Chi Wang, Shih-Ho Wang, Tsan-Shiun Lin, Yueh-Wei Liu, Chin-Hsiang Yang, Chee-Chien Yong, King-Wah Chiu, Bruno Jawan, Hock-Liew Eng, Chao-Long Chen.   

Abstract

Portal vein (PV) complications after living donor liver transplant (LDLT) have been a major concern in pediatric liver transplantation. The incidence of PV complications is more in pediatric (0%-33%) than in adult recipients. Early diagnosis and treatment of PV complications may ensure optimal graft function and good recipient survival. Small preoperation PV size (<4 mm) and slow portal flow (<10 cm/s) combined with lower hepatic artery resistance index (<0.65) are strong warning signs that may predict the development of post LDLT PV complications. Portal vein angioplasty/stenting is conventionally performed through the percutaneous transhepatic approach; however, this can also be performed through transjugular, trans-splenic, and intraoperative approaches. Depending on the situation, using optimal method is the key point to minimize complication (5%) and gain high success rate (80%). PV occlusion of greater than 1 year with cavernous transformation seems to be a factor causing technical failure. Good patency rate (100%) with self-expandable metallic stents was noted in long-term follow-up. In conclusion, PV stent placement is an effective, long-term treatment modality to manage PV complications after pediatric LDLT. Early diagnosis and treatment are essential to maximize the use of stent placement and achieve good success rates.

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Year:  2014        PMID: 24849830     DOI: 10.1097/01.tp.0000446272.05687.ce

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  2 in total

Review 1.  Imaging in pediatric liver transplantation.

Authors:  L Monti; G Soglia; P Tomà
Journal:  Radiol Med       Date:  2016-02-24       Impact factor: 3.469

2.  Complete portal vein occlusion after cyanoacrylate sclerotherapy in biliary atresia treated by living donor liver transplantation with intraoperative portal vein stenting via segment 4 portal vein stump.

Authors:  Chao-Long Chen; Yu-Fan Cheng; Hsin-You Ou; Chee-Chien Yong; Tsan-Shiun Lin; Shih-Ho Wang; Chih-Che Lin; Allan M Concejero
Journal:  Hepatobiliary Surg Nutr       Date:  2018-08       Impact factor: 7.293

  2 in total

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