Literature DB >> 24849494

Trace amines and cocaine abuse.

Jun-Xu Li1.   

Abstract

Cocaine addiction remains a clinical challenge with no effective pharmacotherapy available. Trace amine associated receptor (TAAR) 1 represents a promising drug target for the modulation of dopaminergic system and stimulant abuse. This Viewpoint discusses the emerging data which strongly suggest that TAAR 1 functions as a molecular "brake" that controls the addiction-related effects of cocaine and could be a novel drug target for the development of efficacious pharmacotherapy to treat cocaine addiction.

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Year:  2014        PMID： 24849494      PMCID： PMC4102960          DOI： 10.1021/cn500104s

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN： 1948-7193            Impact factor:   4.418


  5 in total

1.  A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight.

Authors:  F G Revel; J-L Moreau; B Pouzet; R Mory; A Bradaia; D Buchy; V Metzler; S Chaboz; K Groebke Zbinden; G Galley; R D Norcross; D Tuerck; A Bruns; S R Morairty; T S Kilduff; T L Wallace; C Risterucci; J G Wettstein; M C Hoener
Journal:  Mol Psychiatry       Date:  2012-05-29       Impact factor: 15.992

2.  Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics.

Authors:  Florent G Revel; Jean-Luc Moreau; Raul R Gainetdinov; Antonio Ferragud; Clara Velázquez-Sánchez; Tatyana D Sotnikova; Stephen R Morairty; Anja Harmeier; Katrin Groebke Zbinden; Roger D Norcross; Amyaouch Bradaia; Thomas S Kilduff; Barbara Biemans; Bruno Pouzet; Marc G Caron; Juan J Canales; Tanya L Wallace; Joseph G Wettstein; Marius C Hoener
Journal:  Biol Psychiatry       Date:  2012-06-16       Impact factor: 13.382

3.  Effects of the trace amine-associated receptor 1 agonist RO5263397 on abuse-related effects of cocaine in rats.

Authors:  David A Thorn; Li Jing; Yanyan Qiu; Amy M Gancarz-Kausch; Chad M Galuska; David M Dietz; Yanan Zhang; Jun-Xu Li
Journal:  Neuropsychopharmacology       Date:  2014-04-18       Impact factor: 7.853

4.  Activation of the trace amine-associated receptor 1 prevents relapse to cocaine seeking.

Authors:  Yui Pei; Jungah Lee; Damiana Leo; Raul R Gainetdinov; Marius C Hoener; Juan J Canales
Journal:  Neuropsychopharmacology       Date:  2014-04-11       Impact factor: 7.853

5.  Trace amine-associated receptor 1 as a monoaminergic modulator in brain.

Authors:  Zhihua Xie; Gregory M Miller
Journal:  Biochem Pharmacol       Date:  2009-05-29       Impact factor: 5.858
  5 in total
  3 in total

1.  Effects of the trace amine associated receptor 1 agonist RO5263397 on abuse-related behavioral indices of methamphetamine in rats.

Authors:  Li Jing; Yanan Zhang; Jun-Xu Li
Journal:  Int J Neuropsychopharmacol       Date:  2014-10-31       Impact factor: 5.176

Review 2.  Depressive disorders: Treatment failures and poor prognosis over the last 50 years.

Authors:  Thomas P Blackburn
Journal:  Pharmacol Res Perspect       Date:  2019-05-03

3.  Effects of Trace Amine-associated Receptor 1 Agonists on the Expression, Reconsolidation, and Extinction of Cocaine Reward Memory.

Authors:  Jian-Feng Liu; David A Thorn; Yanan Zhang; Jun-Xu Li
Journal:  Int J Neuropsychopharmacol       Date:  2016-07-05       Impact factor: 5.176
  3 in total

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