Literature DB >> 24847183

A SPECIAL MEETING REVIEW EDITION: Advances in the Treatment of Hepatitis C Virus Infection From AASLD 2012: The 63rd Annual Meeting of the American Association for the Study of Liver DiseasesNovember 9-13, 2012 • Boston, MassachusettsSpecial Reporting on:• Timing and Magnitude of Ribavirin Dose Reduction Do Not Impact SVR Rates with Boceprevir Plus Peginterferon α and Ribavirin• A 12-Week Interferon-Free Treatment Regimen with ABT-450/r, ABT-267, ABT-333, and Ribavirin Achieves High SVR12 Rates• High Rate of SVR with the All-Oral Combination of Daclatasvir Plus Sofosbuvir with or without Ribavirin• An Interferon-Free, Ribavirin-Free 12-Week Regimen of Daclatasvir, Asunaprevir, and BMS-791325 Achieved High SVR4 RatesPLUS Meeting Abstract Summaries With Expert Commentary by: Fred Poordad, MDUniversity of San Antonio Health Science CenterSan Antonio, Texas.

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Abstract

Entities:  

Year:  2013        PMID: 24847183      PMCID: PMC4027897     

Source DB:  PubMed          Journal:  Gastroenterol Hepatol (N Y)        ISSN: 1554-7914


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  6 in total

1.  Genotype and subtype profiling of PSI-7977 as a nucleotide inhibitor of hepatitis C virus.

Authors:  Angela M Lam; Christine Espiritu; Shalini Bansal; Holly M Micolochick Steuer; Congrong Niu; Veronique Zennou; Meg Keilman; Yuao Zhu; Shuiyun Lan; Michael J Otto; Phillip A Furman
Journal:  Antimicrob Agents Chemother       Date:  2012-03-19       Impact factor: 5.191

2.  Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial.

Authors:  Stanislas Pol; Reem H Ghalib; Vinod K Rustgi; Claudia Martorell; Greg T Everson; Harvey A Tatum; Christophe Hézode; Joseph K Lim; Jean-Pierre Bronowicki; Gary A Abrams; Norbert Bräu; David W Morris; Paul J Thuluvath; Robert W Reindollar; Philip D Yin; Ulysses Diva; Robert Hindes; Fiona McPhee; Dennis Hernandez; Megan Wind-Rotolo; Eric A Hughes; Steven Schnittman
Journal:  Lancet Infect Dis       Date:  2012-06-18       Impact factor: 25.071

3.  Multiple ascending dose study of BMS-790052, a nonstructural protein 5A replication complex inhibitor, in patients infected with hepatitis C virus genotype 1.

Authors:  Richard E Nettles; Min Gao; Marc Bifano; Ellen Chung; Anna Persson; Thomas C Marbury; Ronald Goldwater; Michael P DeMicco; Maribel Rodriguez-Torres; Apinya Vutikullird; Ernesto Fuentes; Eric Lawitz; Juan Carlos Lopez-Talavera; Dennis M Grasela
Journal:  Hepatology       Date:  2011-12       Impact factor: 17.425

4.  Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032).

Authors:  Fiona McPhee; Amy K Sheaffer; Jacques Friborg; Dennis Hernandez; Paul Falk; Guangzhi Zhai; Steven Levine; Susan Chaniewski; Fei Yu; Diana Barry; Chaoqun Chen; Min S Lee; Kathy Mosure; Li-Qiang Sun; Michael Sinz; Nicholas A Meanwell; Richard J Colonno; Jay Knipe; Paul Scola
Journal:  Antimicrob Agents Chemother       Date:  2012-08-06       Impact factor: 5.191

5.  Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus.

Authors:  Michael J Sofia; Donghui Bao; Wonsuk Chang; Jinfa Du; Dhanapalan Nagarathnam; Suguna Rachakonda; P Ganapati Reddy; Bruce S Ross; Peiyuan Wang; Hai-Ren Zhang; Shalini Bansal; Christine Espiritu; Meg Keilman; Angela M Lam; Holly M Micolochick Steuer; Congrong Niu; Michael J Otto; Phillip A Furman
Journal:  J Med Chem       Date:  2010-10-14       Impact factor: 7.446

6.  Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect.

Authors:  Min Gao; Richard E Nettles; Makonen Belema; Lawrence B Snyder; Van N Nguyen; Robert A Fridell; Michael H Serrano-Wu; David R Langley; Jin-Hua Sun; Donald R O'Boyle; Julie A Lemm; Chunfu Wang; Jay O Knipe; Caly Chien; Richard J Colonno; Dennis M Grasela; Nicholas A Meanwell; Lawrence G Hamann
Journal:  Nature       Date:  2010-04-21       Impact factor: 49.962

  6 in total

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