Literature DB >> 2484570

The effect of diabetes on the molecular localization of maternal and fetal zinc and copper metalloprotein in the rat.

J Y Uriu-Hare1, J S Stern, C L Keen.   

Abstract

The molecular localization of maternal and fetal zinc and copper metalloproteins in diabetic and control rats was studied. Compared to controls, liver and kidneys of diabetic dams showed an increased concentration of zinc and copper that was associated with metallothionein. In contrast, fetuses of diabetic dams had lower zinc and metallothionein levels than fetuses from controls. The abnormal maternal trace element metabolism seen with diabetes resulted in alterations of zinc uptake and/or retention of their fetuses.

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Year:  1988        PMID: 2484570     DOI: 10.1007/bf02917490

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  20 in total

1.  Lipid peroxide level in plasma of diabetic patients.

Authors:  Y Sato; N Hotta; N Sakamoto; S Matsuoka; N Ohishi; K Yagi
Journal:  Biochem Med       Date:  1979-02

Review 2.  Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin.

Authors:  R J Cousins
Journal:  Physiol Rev       Date:  1985-04       Impact factor: 37.312

3.  Gestational zinc deprivation in mice: persistence of immunodeficiency for three generations.

Authors:  R S Beach; M E Gershwin; L S Hurley
Journal:  Science       Date:  1982-10-29       Impact factor: 47.728

4.  Increased lipoperoxide value and glutathione peroxidase activity in blood plasma of type 2 (non-insulin-dependent) diabetic women.

Authors:  H Kaji; M Kurasaki; K Ito; T Saito; K Saito; T Niioka; Y Kojima; Y Ohsaki; H Ide; M Tsuji
Journal:  Klin Wochenschr       Date:  1985-08-16

5.  The effect of maternal diabetes on trace element status and fetal development in the rat.

Authors:  J Y Uriu-Hare; J S Stern; G M Reaven; C L Keen
Journal:  Diabetes       Date:  1985-10       Impact factor: 9.461

6.  Copper toxicosis and tolerance in the rat. I--Changes in copper content of the liver and kidney.

Authors:  S Haywood
Journal:  J Pathol       Date:  1985-02       Impact factor: 7.996

7.  Placental growth and glycogen metabolism in streptozotocin diabetic rats.

Authors:  I H Gewolb; C Barrett; J B Warshaw
Journal:  Pediatr Res       Date:  1983-07       Impact factor: 3.756

8.  Influence of spontaneous diabetes on tissue status of zinc, copper, and manganese in the BB Wistar rat.

Authors:  M L Failla; C Y Gardell
Journal:  Proc Soc Exp Biol Med       Date:  1985-11

9.  Diabetes in pregnancy: decreased placental blood flow and disturbed fetal development in the rat.

Authors:  U J Eriksson; L Jansson
Journal:  Pediatr Res       Date:  1984-08       Impact factor: 3.756

10.  Uteroplacental blood flow in diabetic pregnancy: measurements with indium 113m and a computer-linked gamma camera.

Authors:  L Nylund; N O Lunell; R Lewander; B Persson; B Sarby
Journal:  Am J Obstet Gynecol       Date:  1982-10-01       Impact factor: 8.661

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