| Literature DB >> 24845669 |
Maria Vera1, Robert H Singer2.
Abstract
Limited chromosome mobility has been observed in mammalian interphase nuclei. Live imaging shows unidirectional and actin-dependent movement of HSP70 loci towards speckles upon heat shock, resulting in enhanced transcription. This adds further impetus to understanding compartmentalization of function in the nucleus.Entities:
Mesh:
Year: 2014 PMID: 24845669 PMCID: PMC4156153 DOI: 10.1016/j.cub.2014.03.070
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834