Jong Rak Lee1, Kyung Rim Sung1, Seungbong Han2. 1. Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea. 2. Division of Biostatistics, Center for Medical Research and Information, College of Medicine, Asan Medical Center, Seoul, Korea.
Abstract
PURPOSE: To investigate features of the anterior segment (AS) of the affected eye compared to the fellow eye within the same patient in acute primary angle closure (APAC). METHODS: Thirty-six patients with unilateral APAC were imaged with AS optical coherence tomography (OCT) before medical or laser treatment for the acute attack. Anterior chamber depth (ACD), iris curvature (IC), iris thickness at 750 μm from the scleral spur (IT750), lens vault (LV), anterior chamber area (ACA), and iris area were estimated by using ImageJ software (version 1.46). Conditional logistic regression analysis was performed to find the associated factors with the prediction of APAC. RESULTS: When compared to fellow eyes, affected eyes showed significantly shallower ACD (1.90 ± 0.24 and 1.55 ± 0.30 mm, respectively; P < 0.001), smaller ACA (12.96 ± 2.38 and 10.41 ± 2.34 mm(2), respectively; P < 0.001), and greater LV (1.06 ± 0.31 and 1.26 ± 0.36 mm, respectively; P = 0.017). Less IC (odds ratio [OR]*100: 0.935 [95% confidence interval: 0.894, 0.979], P = 0.004) and IT750 (OR*100: 0.904 [0.8294, 0.987], P = 0.024), greater central corneal thickness (OR*100: 2.100 [1.245, 3.542], P = 0.005), greater LV (OR: 66.7 [2.529, 1761.3], P = 0.012), less ACA (OR: 0.386 [0.193, 0.774], P = 0.007), and less ACD (OR*100: 0.912 [0.855, 0.972], P = 0.005) were significantly associated with prediction of APAC. CONCLUSIONS: Greater LV was the most prominent feature of affected eyes compared to fellow eyes in APAC patients when assessed by AS OCT. This may play a role in the development of acute attack in primary angle closure. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.
PURPOSE: To investigate features of the anterior segment (AS) of the affected eye compared to the fellow eye within the same patient in acute primary angle closure (APAC). METHODS: Thirty-six patients with unilateral APAC were imaged with AS optical coherence tomography (OCT) before medical or laser treatment for the acute attack. Anterior chamber depth (ACD), iris curvature (IC), iris thickness at 750 μm from the scleral spur (IT750), lens vault (LV), anterior chamber area (ACA), and iris area were estimated by using ImageJ software (version 1.46). Conditional logistic regression analysis was performed to find the associated factors with the prediction of APAC. RESULTS: When compared to fellow eyes, affected eyes showed significantly shallower ACD (1.90 ± 0.24 and 1.55 ± 0.30 mm, respectively; P < 0.001), smaller ACA (12.96 ± 2.38 and 10.41 ± 2.34 mm(2), respectively; P < 0.001), and greater LV (1.06 ± 0.31 and 1.26 ± 0.36 mm, respectively; P = 0.017). Less IC (odds ratio [OR]*100: 0.935 [95% confidence interval: 0.894, 0.979], P = 0.004) and IT750 (OR*100: 0.904 [0.8294, 0.987], P = 0.024), greater central corneal thickness (OR*100: 2.100 [1.245, 3.542], P = 0.005), greater LV (OR: 66.7 [2.529, 1761.3], P = 0.012), less ACA (OR: 0.386 [0.193, 0.774], P = 0.007), and less ACD (OR*100: 0.912 [0.855, 0.972], P = 0.005) were significantly associated with prediction of APAC. CONCLUSIONS: Greater LV was the most prominent feature of affected eyes compared to fellow eyes in APAC patients when assessed by AS OCT. This may play a role in the development of acute attack in primary angle closure. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.
Authors: Han Seok Park; Joon Mo Kim; Seong Hee Shim; Hyun Tae Kim; Jeong Hun Bae; Chul Young Choi; Ki Ho Park Journal: Jpn J Ophthalmol Date: 2015-08-04 Impact factor: 2.447