Literature DB >> 24845517

Gene therapy in India: a focus.

Sarvani Chodisetty1, Everette Jacob Remington Nelson.   

Abstract

Gene therapy refers to the treatment of genetic diseases using normal copies of the defective genes. It has the potential to cure any genetic disease with long-lasting therapeutic benefits. It remained an enigma for a long period of time, which was followed by a series of setbacks in the late 1990s. Gene therapy has re-emerged as a therapeutic option with reports of success from recent clinical studies. The United States and Europe has been pioneers in this field for over two decades. Recently, reports of gene therapy have started coming in from Asian countries like China, Japan and Korea. This review focuses on the current status of gene therapy in India.

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Year:  2014        PMID: 24845517     DOI: 10.1007/s12038-014-9431-2

Source DB:  PubMed          Journal:  J Biosci        ISSN: 0250-5991            Impact factor:   1.826


  21 in total

1.  Mode of cell death associated with adenovirus-mediated suicide gene therapy in HNSCC tumor model.

Authors:  Deepika Srivastava; Ganesh Joshi; Kumaravel Somasundaram; Rita Mulherkar
Journal:  Anticancer Res       Date:  2011-11       Impact factor: 2.480

2.  Effect of suicide gene therapy in combination with immunotherapy on antitumour immune response & tumour regression in a xenograft mouse model for head & neck squamous cell carcinoma.

Authors:  Aditya V Ambade; Ganesh V Joshi; Rita Mulherkar
Journal:  Indian J Med Res       Date:  2010-10       Impact factor: 2.375

3.  Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells.

Authors:  R Dash; I Dmitriev; Z-z Su; S K Bhutia; B Azab; N Vozhilla; A Yacoub; P Dent; D T Curiel; D Sarkar; P B Fisher
Journal:  Cancer Gene Ther       Date:  2010-02-12       Impact factor: 5.987

4.  Targeted cytosolic delivery of hydrogel nanoparticles into HepG2 cells through engineered Sendai viral envelopes.

Authors:  Siddhartha S Jana; Dhruba J Bharali; Prashant Mani; Amarnath Maitra; Chhitar M Gupta; Debi P Sarkar
Journal:  FEBS Lett       Date:  2002-03-27       Impact factor: 4.124

5.  Efficient transgene reconstitution with hybrid dual AAV vectors carrying the minimized bridging sequences.

Authors:  Arkasubhra Ghosh; Yongping Yue; Dongsheng Duan
Journal:  Hum Gene Ther       Date:  2010-12-12       Impact factor: 5.695

6.  An engineered EBV vector expressing human factor VIII and von Willebrand factor in cultured B-cells.

Authors:  Utpal Basu; Subrata Banerjee
Journal:  J Gene Med       Date:  2004-07       Impact factor: 4.565

7.  Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir.

Authors:  E H Oldfield; Z Ram; K W Culver; R M Blaese; H L DeVroom; W F Anderson
Journal:  Hum Gene Ther       Date:  1993-02       Impact factor: 5.695

8.  Mesenchymal stem cells expressing osteogenic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect.

Authors:  Sanjay Kumar; Chao Wan; Girish Ramaswamy; Thomas L Clemens; Selvarangan Ponnazhagan
Journal:  Mol Ther       Date:  2010-01-12       Impact factor: 11.454

9.  Therapeutic potential of genetically modified adult stem cells for osteopenia.

Authors:  S Kumar; T R Nagy; S Ponnazhagan
Journal:  Gene Ther       Date:  2009-09-10       Impact factor: 5.250

10.  Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy.

Authors:  Dwaipayan Sen; Balaji Balakrishnan; Nishanth Gabriel; Prachi Agrawal; Vaani Roshini; Rekha Samuel; Alok Srivastava; Giridhara R Jayandharan
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379

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  2 in total

1.  Multicenter Outcome of Hematopoietic Stem Cell Transplantation for Primary Immune Deficiency Disorders in India.

Authors:  Revathi Raj; Fouzia N Aboobacker; Satya Prakash Yadav; Ramya Uppuluri; Sunil Bhat; Dharma Choudhry; Vikas Dua; Gaurav Kharya; Neha Rastogi; Mansi Sachdev; Vipin Khandelwal; Venkateswaran Swaminathan; Atish Bakane; Balasubramaniam Ramakrishnan; Biju George
Journal:  Front Immunol       Date:  2021-01-08       Impact factor: 7.561

2.  A bibliometric analysis of research on genetic retinal diseases done in India.

Authors:  Ravichandran Kumaragurupari; Chitaranjan Mishra
Journal:  Indian J Ophthalmol       Date:  2022-07       Impact factor: 2.969

  2 in total

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