Literature DB >> 2484541

Effects of salicylate and zinc deficiency on the serum concentrations of magnesium, calcium, and parathyroid hormone.

T Günther1, V Höllriegl, J Vormann.   

Abstract

Oral application of 700 mg/kg salicylic acid to pregnant and non-pregnant female rats caused an increase of serum Mg2+ and a decrease of serum Ca2+ concentration. The salicylate effect was drastically enhanced by Zn deficiency. The increase in serum Mg2+ is probably caused by the nephrotoxicity of salicylate. The decrease of serum Ca2+ concentration is combined with an increase of parathyroid hormone concentration in serum. Probably, salicylate and Zn deficiency inhibit Ca2+ mobilization by parathyroid hormone in bone.

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Year:  1988        PMID： 2484541     DOI： 10.1007/BF02797097

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  9 in total

1.  Electrolyte distribution in rats following salicylate.

Authors:  J S CHARNOCK; L J OPIT; B S HETZEL
Journal:  Metabolism       Date:  1961-11       Impact factor: 8.694

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 3.  The metallobiochemistry of zinc enzymes.

Authors:  B L Vallee; A Galdes
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1984

Review 4.  Skeletal actions of parathyroid hormone.

Authors:  G Wong
Journal:  Miner Electrolyte Metab       Date:  1982 Sep-Oct

5.  Salicylate effects on proton gradient dissipation by isolated gastric mucosal surface cells.

Authors:  E J Olender; D Woods; R Kozol; D Fromm
Journal:  Proc Soc Exp Biol Med       Date:  1986-11

6.  Fetal toxicity and hypocalcemia induced by acetylsalicylic acid analogues.

Authors:  H Saito; A Yokoyama; S Takeno; T Sakai; K Ueno; H Masumura; H Kitagawa
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1982-11

7.  [Effect of sodium salicylate on renal handling of calcium, phosphate and magnesium].

Authors:  S Yamada; T Morohashi
Journal:  Nihon Yakurigaku Zasshi       Date:  1986-11

8.  Role of carbonic anhydrase in bone resorption induced by 1,25 dihydroxyvitamin D3 in vitro.

Authors:  G E Hall; A D Kenny
Journal:  Calcif Tissue Int       Date:  1985-03       Impact factor: 4.333

9.  Membrane alterations in magnesium-deficiency-induced malignant T cell lymphoma.

Authors:  T Günther; J Vormann; H J Merker; R Averdunk; H W Peter; K Wonigeit
Journal:  Magnesium       Date:  1984
  9 in total
  3 in total

Review 1.  Clinical implications of trace elements in endocrinology.

Authors:  J Neve
Journal:  Biol Trace Elem Res       Date:  1992 Jan-Mar       Impact factor: 3.738

2.  Enhancement of maternal and fetal nephrotoxicity of salicylate by zinc deficiency. Morphological, enzyme histochemical and immunohistochemical studies.

Authors:  R Gossrau; T Günther; H J Merker; R Graf
Journal:  Histochemistry       Date:  1988

3.  Protection against salicylate-induced hepatic injury by zinc. A histochemical and biochemical study.

Authors:  T Günther; R Gossrau; J Vormann; M Ruhnke
Journal:  Histochem J       Date:  1991-02
  3 in total

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