WHAT IS KNOWN AND OBJECTIVE: Cannabidiol (CBD) is the main non-psychotropic component of the Cannabis sativa plant. REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of muscle atonia during REM sleep associated with nightmares and active behaviour during dreaming. We have described the effects of CBD in RBD symptoms in patients with Parkinson's disease. CASES SUMMARY: Four patients treated with CBD had prompt and substantial reduction in the frequency of RBD-related events without side effects. WHAT IS NEW AND CONCLUSION: This case series indicates that CBD is able to control the symptoms of RBD.
WHAT IS KNOWN AND OBJECTIVE: Cannabidiol (CBD) is the main non-psychotropic component of the Cannabis sativa plant. REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of muscle atonia during REM sleep associated with nightmares and active behaviour during dreaming. We have described the effects of CBD in RBD symptoms in patients with Parkinson's disease. CASES SUMMARY: Four patients treated with CBD had prompt and substantial reduction in the frequency of RBD-related events without side effects. WHAT IS NEW AND CONCLUSION: This case series indicates that CBD is able to control the symptoms of RBD.
Authors: José Alexandre S Crippa; Antonio Waldo Zuardi; Jaime Eduardo Cecílio Hallak; Bruna Miyazawa; Sandra Aparecido Bernardo; Carmem Maria Donaduzzi; Silvane Guzzi; Wagner Alex Jann Favreto; Alline Campos; Maria Eugênia C Queiroz; Francisco S Guimarães; Patrícia Moura da Rosa Zimmermann; Letícia Mello Rechia; Volnei Jose Tondo Filho; Liberato Brum Junior Journal: Cannabis Cannabinoid Res Date: 2020-02-27
Authors: José Alexandre S Crippa; Jaime E C Hallak; Antônio W Zuardi; Francisco S Guimarães; Vitor Tumas; Rafael G Dos Santos Journal: Eur Arch Psychiatry Clin Neurosci Date: 2019-01-31 Impact factor: 5.270