Literature DB >> 24844906

The value of a tumor bank in the development of cancer research in Brazil: 13 years of experience at the a C camargo hospital.

Antonio Hugo Jose Froes Marques Campos1, Andre Abreu Silva, Louise Danielle De Carvalho Mota, Eloisa Ribeiro Olivieri, Vera Cristina Prescinoti, Diogo Patrão, Luiz Paulo Camargo, Helena Brentani, Dirce Maria Carraro, Ricardo Renzo Brentani, Fernando Augusto Soares.   

Abstract

This article discusses the importance of biobanking to health research advancement in developing countries by analyzing the impact of the establishment of a tumor bank at the A C Camargo Hospital, a cancer care and research center located in Sao Paulo, Brazil. For the past 13 years, the human biological samples provided by the tumor bank have been used by investigators to study various types of cancer. We analyze the impact of biobanking in the overall quality of research projects performed at our institution. We also summarize the main findings of these investigations focusing on breast, prostate, head-neck, and gastroesophageal tumors, as well as the lessons learned over these years. We conclude that biobanking should be part of the strategy employed by scientists and research institutions dedicated to the study of human diseases.

Entities:  

Year:  2012        PMID: 24844906     DOI: 10.1089/bio.2011.0032

Source DB:  PubMed          Journal:  Biopreserv Biobank        ISSN: 1947-5543            Impact factor:   2.300


  7 in total

1.  Germline CDKN2A mutations in Brazilian patients of hereditary cutaneous melanoma.

Authors:  Alexandre Leon Ribeiro de Ávila; Ana Cristina Victorino Krepischi; Luciana Facure Moredo; Talita Ferreira Marques Aguiar; Felipe Carneiro da Silva; Bianca Costa Soares de Sá; Amanda França de Nóbrega; Maria Isabel Waddington Achatz; João Pedreira Duprat; Gilles Landman; Dirce Maria Carraro
Journal:  Fam Cancer       Date:  2014-12       Impact factor: 2.375

2.  Phosphodiesterase sequence variants may predispose to prostate cancer.

Authors:  Rodrigo B de Alexandre; Anelia D Horvath; Eva Szarek; Allison D Manning; Leticia F Leal; Fabio Kardauke; Jonathan A Epstein; Dirce M Carraro; Fernando A Soares; Tatiyana V Apanasovich; Constantine A Stratakis; Fabio R Faucz
Journal:  Endocr Relat Cancer       Date:  2015-05-15       Impact factor: 5.678

3.  Lymphovascular invasion and histologic grade are associated with specific genomic profiles in invasive carcinomas of the breast.

Authors:  Felipe Fidalgo; Tatiane Cristina Rodrigues; Mabel Pinilla; Amanda Gonçalves Silva; Maria do Socorro Maciel; Carla Rosenberg; Victor Piana de Andrade; Dirce Maria Carraro; Ana Cristina Victorino Krepischi
Journal:  Tumour Biol       Date:  2014-11-13

4.  DNA Methylation Levels of Melanoma Risk Genes Are Associated with Clinical Characteristics of Melanoma Patients.

Authors:  Érica S S de Araújo; Dimitrius T Pramio; André Y Kashiwabara; Paula C Pennacchi; Silvya S Maria-Engler; Maria I Achatz; Antonio H J F M Campos; João P Duprat; Carla Rosenberg; Dirce M Carraro; Ana C V Krepischi
Journal:  Biomed Res Int       Date:  2015-04-12       Impact factor: 3.411

5.  A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease.

Authors:  Elisa Napolitano Ferreira; Bruna Durães Figueiredo Barros; Jorge Estefano de Souza; Renan Valieris Almeida; Giovana Tardin Torrezan; Sheila Garcia; Ana Cristina Victorino Krepischi; Celso Abdon Lopes de Mello; Isabela Werneck da Cunha; Clóvis Antonio Lopes Pinto; Fernando Augusto Soares; Emmanuel Dias-Neto; Ademar Lopes; Sandro José de Souza; Dirce Maria Carraro
Journal:  Hum Genomics       Date:  2016-11-18       Impact factor: 4.639

6.  Insights Into the Somatic Mutation Burden of Hepatoblastomas From Brazilian Patients.

Authors:  Talita Ferreira Marques Aguiar; Maria Prates Rivas; Silvia Costa; Mariana Maschietto; Tatiane Rodrigues; Juliana Sobral de Barros; Anne Caroline Barbosa; Renan Valieris; Gustavo R Fernandes; Debora R Bertola; Monica Cypriano; Silvia Regina Caminada de Toledo; Angela Major; Israel Tojal; Maria Lúcia de Pinho Apezzato; Dirce Maria Carraro; Carla Rosenberg; Cecilia Maria Lima da Costa; Isabela W Cunha; Stephen Frederick Sarabia; Dolores-López Terrada; Ana Cristina Victorino Krepischi
Journal:  Front Oncol       Date:  2020-05-05       Impact factor: 6.244

7.  Xeroderma pigmentosum: low prevalence of germline XPA mutations in a Brazilian XP population.

Authors:  Karina Miranda Santiago; Amanda França de Nóbrega; Rafael Malagoli Rocha; Silvia Regina Rogatto; Maria Isabel Achatz
Journal:  Int J Mol Sci       Date:  2015-04-22       Impact factor: 5.923

  7 in total

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