Nileshkumar J Patel1, Abhishek Deshmukh2, Sadip Pant2, Vikas Singh2, Nilay Patel2, Shilpkumar Arora2, Neeraj Shah2, Ankit Chothani2, Ghanshyambhai T Savani2, Kathan Mehta2, Valay Parikh2, Ankit Rathod2, Apurva O Badheka2, James Lafferty2, Marcin Kowalski2, Jawahar L Mehta2, Raul D Mitrani2, Juan F Viles-Gonzalez2, Hakan Paydak2. 1. From the Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., V.P., J.L., M.K.); University of Arkansas, Little Rock (A.D., S.P., J.L.M., H.P.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., R.D.M., J.F.V.-G.); Detroit Medical Centre, Detroit, MI (N.P., S.A., A.O.B.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside, Pittsburgh, PA (K.M.); and Cedar-Sinai Medical Center, Los Angeles, CA (A.R.). dr.nilesh.j.patel@gmail.com. 2. From the Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., V.P., J.L., M.K.); University of Arkansas, Little Rock (A.D., S.P., J.L.M., H.P.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., R.D.M., J.F.V.-G.); Detroit Medical Centre, Detroit, MI (N.P., S.A., A.O.B.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside, Pittsburgh, PA (K.M.); and Cedar-Sinai Medical Center, Los Angeles, CA (A.R.).
Abstract
BACKGROUND: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. The associated morbidity and mortality make AF a major public health burden. Hospitalizations account for the majority of the economic cost burden associated with AF. The main objective of this study is to examine the trends of AF-related hospitalizations in the United States and to compare patient characteristics, outcomes, and comorbid diagnoses. METHODS AND RESULTS: With the use of the Nationwide Inpatient Sample from 2000 through 2010, we identified AF-related hospitalizations using International Classification of Diseases, 9th Revision, Clinical Modification code 427.31 as the principal discharge diagnosis. Overall AF hospitalizations increased by 23% from 2000 to 2010, particularly in patients ≥65 years of age. The most frequent coexisting conditions were hypertension (60.0%), diabetes mellitus (21.5%), and chronic pulmonary disease (20.0%). Overall in-hospital mortality was 1%. The mortality rate was highest in the group of patients ≥80 years of age (1.9%) and in the group of patients with concomitant heart failure (8.2%). In-hospital mortality rate decreased significantly from 1.2% in 2000 to 0.9% in 2010 (29.2% decrease; P<0.001). Although there was no significant change in mean length of stay, mean cost of AF hospitalization increased significantly from $6410 in 2001 to $8439 in 2010 (24.0% increase; P<0.001). CONCLUSIONS: Hospitalization rates for AF have increased exponentially among US adults from 2000 to 2010. The proportion of comorbid chronic diseases has also increased significantly. The last decade has witnessed an overall decline in hospital mortality; however, the hospitalization cost has significantly increased.
BACKGROUND:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. The associated morbidity and mortality make AF a major public health burden. Hospitalizations account for the majority of the economic cost burden associated with AF. The main objective of this study is to examine the trends of AF-related hospitalizations in the United States and to compare patient characteristics, outcomes, and comorbid diagnoses. METHODS AND RESULTS: With the use of the Nationwide Inpatient Sample from 2000 through 2010, we identified AF-related hospitalizations using International Classification of Diseases, 9th Revision, Clinical Modification code 427.31 as the principal discharge diagnosis. Overall AF hospitalizations increased by 23% from 2000 to 2010, particularly in patients ≥65 years of age. The most frequent coexisting conditions were hypertension (60.0%), diabetes mellitus (21.5%), and chronic pulmonary disease (20.0%). Overall in-hospital mortality was 1%. The mortality rate was highest in the group of patients ≥80 years of age (1.9%) and in the group of patients with concomitant heart failure (8.2%). In-hospital mortality rate decreased significantly from 1.2% in 2000 to 0.9% in 2010 (29.2% decrease; P<0.001). Although there was no significant change in mean length of stay, mean cost of AF hospitalization increased significantly from $6410 in 2001 to $8439 in 2010 (24.0% increase; P<0.001). CONCLUSIONS: Hospitalization rates for AF have increased exponentially among US adults from 2000 to 2010. The proportion of comorbid chronic diseases has also increased significantly. The last decade has witnessed an overall decline in hospital mortality; however, the hospitalization cost has significantly increased.
Authors: Sian Yik Lim; Na Lu; Amar Oza; Mark Fisher; Sharan K Rai; Mariano E Menendez; Hyon K Choi Journal: JAMA Date: 2016-06-07 Impact factor: 56.272
Authors: Michael M McNeil; Susan K Duderstadt; Jennifer F Sabatier; Gina G Ma; Jonathan Duffy Journal: Hum Vaccin Immunother Date: 2019-01-08 Impact factor: 3.452
Authors: Fadar Oliver Otite; Priyank Khandelwal; Seemant Chaturvedi; Jose G Romano; Ralph L Sacco; Amer M Malik Journal: Neurology Date: 2016-10-12 Impact factor: 9.910
Authors: Tyler W Barrett; Alan B Storrow; Cathy A Jenkins; Robert L Abraham; Dandan Liu; Karen F Miller; Kelly M Moser; Stephan Russ; Dan M Roden; Frank E Harrell; Dawood Darbar Journal: Am J Cardiol Date: 2015-01-06 Impact factor: 2.778
Authors: Tyler W Barrett; Marian J Vermeulen; Wesley H Self; Cathy A Jenkins; Allison J Ferreira; Clare L Atzema Journal: J Am Coll Cardiol Date: 2015-05-26 Impact factor: 24.094