Seo-Young An1, Jae-Seo Lee2, Erika Benavides3, Alireza Aminlari4, Neville J McDonald5, Paul C Edwards6, Min-Suk Heo7, Hong-In Shin8, Jin-Woo Park9, Jae-Kwang Jung10, Karp-Shik Choi11, Chang-Hyeon An12. 1. Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. 2. Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Dental Science Institute, Chonnam National University, Gwangju, Republic of Korea. 3. Clinical Assistant Professor, Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA. 4. Adjunct Lecturer, Division of Endodontics, University of Michigan, Ann Arbor, Michigan and Specialist Endodontic Private Practice, Farmington Hills, Michigan, USA. 5. Clinical Professor, Division Head and Graduate Program Director, Endodontics, University of Michigan, Ann Arbor, Michigan, USA. 6. Professor, Department of Oral Pathology, Medicine and Radiology, Indiana University School of Dentistry, Indianapolis, Indiana, USA. 7. Professor, Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea. 8. Associate Professor, Department of Oral Pathology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. 9. Assistant Professor, Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. 10. Assistant Professor, Department of Oral Medicine, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. 11. Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. Electronic address: ksichoi@knu.ac.kr. 12. Associate Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. Electronic address: chan@knu.ac.kr.
Abstract
OBJECTIVES: This study contributes three well-documented cases of multiple simple bone cysts (SBCs) of the jaws and reviews previously published cases. STUDY DESIGN: A comprehensive literature search of multiple SBCs was conducted using the PubMed database. Synonyms of SBC were used as search key words in combination with "mandible or jaw," "bilateral, multiple, multifocal, atypical, and unusual." RESULTS: A total of 34 cases of multiple SBCs (including two asynchronous cases) were identified, including the three new cases reported here. Multiple SBCs primarily occurred in the second decade (52.9%) and bilaterally in the posterior mandible. Lesions demonstrated female predominance (1.8:1) and were frequently accompanied by bony expansion (44.1%) and a multilocular radiolucent appearance (20.6 %). Recurrence was reported in three patients (mean age: 39.3 years old). CONCLUSION: Knowledge of the clinical and radiographic features of multiple SBCs is important in the diagnosis and management of this entity.
OBJECTIVES: This study contributes three well-documented cases of multiple simple bone cysts (SBCs) of the jaws and reviews previously published cases. STUDY DESIGN: A comprehensive literature search of multiple SBCs was conducted using the PubMed database. Synonyms of SBC were used as search key words in combination with "mandible or jaw," "bilateral, multiple, multifocal, atypical, and unusual." RESULTS: A total of 34 cases of multiple SBCs (including two asynchronous cases) were identified, including the three new cases reported here. Multiple SBCs primarily occurred in the second decade (52.9%) and bilaterally in the posterior mandible. Lesions demonstrated female predominance (1.8:1) and were frequently accompanied by bony expansion (44.1%) and a multilocular radiolucent appearance (20.6 %). Recurrence was reported in three patients (mean age: 39.3 years old). CONCLUSION: Knowledge of the clinical and radiographic features of multiple SBCs is important in the diagnosis and management of this entity.