OBJECTIVES: The involvement of arginine-vasopressin (AVP) in animal and human aggression has been well established in the literature. Recent research has shown an association between the minor allele (C) of single-nucleotide polymorphism rs35369693 located on the AVP 1B receptor gene and childhood aggression. MATERIALS AND METHODS: The present study sought to replicate the association between rs35369693 and aggression using a sample of clinically referred children (N=141) with behavioural problems. RESULTS: Analyses confirmed a significant relationship between the minor C allele on rs35369693 and teacher-rated reactive aggression. Although males had significantly greater aggression than females on three of the four measures, sex was not shown to moderate the effect of the C allele on any of the aggression measures. CONCLUSION: These findings reinforce the results from previous research and also suggest that the associations of the AVP 1B receptor may be specific to reactive, emotional rather than proactive or callous types of aggression.
OBJECTIVES: The involvement of arginine-vasopressin (AVP) in animal and humanaggression has been well established in the literature. Recent research has shown an association between the minor allele (C) of single-nucleotide polymorphism rs35369693 located on the AVP 1B receptor gene and childhood aggression. MATERIALS AND METHODS: The present study sought to replicate the association between rs35369693 and aggression using a sample of clinically referred children (N=141) with behavioural problems. RESULTS: Analyses confirmed a significant relationship between the minor C allele on rs35369693 and teacher-rated reactive aggression. Although males had significantly greater aggression than females on three of the four measures, sex was not shown to moderate the effect of the C allele on any of the aggression measures. CONCLUSION: These findings reinforce the results from previous research and also suggest that the associations of the AVP 1B receptor may be specific to reactive, emotional rather than proactive or callous types of aggression.
Authors: Sunday M Francis; Soo-Jeong Kim; Emily Kistner-Griffin; Stephen Guter; Edwin H Cook; Suma Jacob Journal: Front Neurosci Date: 2016-11-22 Impact factor: 4.677
Authors: Maaike Verhagen; Karin J H Verweij; Gerine M A Lodder; Luc Goossens; Karine Verschueren; Karla Van Leeuwen; Wim Van den Noortgate; Stephan Claes; Patricia Bijttebier; Evelien Van Assche; Jaqueline M Vink Journal: J Res Adolesc Date: 2019-01-29
Authors: Sarah K Williams Avram; Heon-Jin Lee; Jarrett Fastman; Adi Cymerblit-Sabba; Adam Smith; Matthew Vincent; June Song; Michael C Granovetter; Su-Hyun Lee; Nicholas I Cilz; Michelle Stackmann; Rahul Chaturvedi; W Scott Young Journal: Front Behav Neurosci Date: 2019-11-08 Impact factor: 3.558