| Literature DB >> 24841115 |
Abstract
The use of Me3SiO(-)/Bu4N(+) as a general activator of organotrimethylsilanes for addition reactions has been established. The broad scope of the method offers trimethylsilanes (including acetate, allyl, propargyl, benzyl, dithiane, heteroaryl, and aryl derivatives) as bench-stable organometallics that can be readily utilized as carbanion equivalents for synthesis. Reactions are achieved at rt without the requirement of specialized precautions that are commonplace for other organometallics.Entities:
Mesh：
Substances：
Year: 2014 PMID： 24841115 DOI： 10.1021/jo5007637
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354