Literature DB >> 24840704

Hepatocellular carcinoma: genome-scale metabolic models for hepatocellular carcinoma.

Roser Pinyol1, Josep M Llovet1.   

Abstract

A new study proposes a modelling strategy to identify reactions, genes and metabolites relevant in hepatocellular carcinoma using in silico and in vivo analyses. The proposed genome-scale metabolic model integrates genomic and proteomic information, and points to statins, among others, as potential chemopreventive and anticancer drugs.

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Year:  2014        PMID: 24840704     DOI: 10.1038/nrgastro.2014.70

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN: 1759-5045            Impact factor:   46.802


  6 in total

1.  Hsa-mir-1269 genetic variant contributes to hepatocellular carcinoma susceptibility through affecting SOX6.

Authors:  Guanying Xiong; Yun Wang; Quchen Ding; Lihua Yang
Journal:  Am J Transl Res       Date:  2015-10-15       Impact factor: 4.060

2.  The Blockage of KCa3.1 Channel Inhibited Proliferation, Migration and Promoted Apoptosis of Human Hepatocellular Carcinoma Cells.

Authors:  Yu Liu; Liang Zhao; Wenya Ma; Xuefeng Cao; Hongyang Chen; Dan Feng; Jing Liang; Kun Yin; Xiaofeng Jiang
Journal:  J Cancer       Date:  2015-05-26       Impact factor: 4.207

3.  A Hopeful Natural Product, Pristimerin, Induces Apoptosis, Cell Cycle Arrest, and Autophagy in Esophageal Cancer Cells.

Authors:  Peng Huang; Li-Ying Sun; Yan-Qiao Zhang
Journal:  Anal Cell Pathol (Amst)       Date:  2019-05-14       Impact factor: 2.916

4.  Multiple Omics Integration Reveals Key Circular RNAs in Hepatocellular Carcinoma.

Authors:  Zi-Li Huang; Xiu-Yan Huang; Jin Huang; Xin-Yu Huang; Yong-Hua Xu; Jian Zhou; Zhao-You Tang
Journal:  Front Oncol       Date:  2021-05-18       Impact factor: 6.244

5.  Knowledge-based analyses reveal new candidate genes associated with risk of hepatitis B virus related hepatocellular carcinoma.

Authors:  Deke Jiang; Jiaen Deng; Changzheng Dong; Xiaopin Ma; Qianyi Xiao; Bin Zhou; Chou Yang; Lin Wei; Carly Conran; S Lilly Zheng; Irene Oi-Lin Ng; Long Yu; Jianfeng Xu; Pak C Sham; Xiaolong Qi; Jinlin Hou; Yuan Ji; Guangwen Cao; Miaoxin Li
Journal:  BMC Cancer       Date:  2020-05-11       Impact factor: 4.430

6.  miR-31 Modulates Liver Cancer HepG2 Cell Apoptosis and Invasion via ROCK1/F-Actin Pathways.

Authors:  Xin Zhang; Lan Xu; Ting Yang
Journal:  Onco Targets Ther       Date:  2020-01-29       Impact factor: 4.147

  6 in total

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