Literature DB >> 24839502

Normal black kidney.

Aliasghar Yarmohamadi1, Ali Reza Akhavan Rezayat1, Bahram Memar2, Hamid Reza Rahimi1, PhD Cand3.   

Abstract

A black kidney has 3 major differential diagnoses: hemosiderosis, lipofuscin pigment and melanotic renal cell carcinoma. Excluding lipofuscin, the other 2 are accompanied by an abnormal renal function. We report on a 25-year-old man who intended to donate a kidney to his cousin. On the operating room table when we incised the left flank region and exposed the kidney, we found a firm and black kidney so the operation was cancelled due to potential vascular injuries. Days after the incomplete procedure, we reviewed the donor's biochemistry and imaging to reassess his renal function, but the results showed quite normal renal function again. The result of Ham test was also negative. Two weeks later, we began the operation, removed the same left kidney and found that it was in the same conditions as it was before. We took the opportunity to send needle biopsies of the kidney for histopathologic analysis. The analysis showed a melanotic kidney without pathological changes in glomeruli and interstitium and vessels. A black kidney may result in hemosiderin, lipofuscin or melanin deposits in the kidney, which can confirm the diagnosis; however, special tests for underlying disease and renal function should be considered. Some causes of black kidney lead to abnormal function, but our patients's kidney returned to normal.

Entities:  

Year:  2014        PMID: 24839502      PMCID: PMC4001663          DOI: 10.5489/cuaj.1207

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  26 in total

1.  Renal haemosiderosis: an unusual presentation of acute renal failure in a patient following heart valve prosthesis.

Authors:  Daniel Ackermann; Bruno Vogt; Mathias Gugger; Hans-Peter Marti
Journal:  Nephrol Dial Transplant       Date:  2004-10       Impact factor: 5.992

2.  Renal hemosiderosis: a case of black kidneys causing renal failure.

Authors:  N Relia; C Kaushik
Journal:  J Postgrad Med       Date:  2010 Jul-Sep       Impact factor: 1.476

3.  Dissecting the evolutionary genetics of iron overload in non-alcoholic fatty liver disease.

Authors:  Felix Stickel; Jochen Hampe
Journal:  J Hepatol       Date:  2010-07-24       Impact factor: 25.083

Review 4.  Analgesic nephropathy: is it caused by multi-analgesic abuse or single substance use?

Authors:  M M Elseviers; M E De Broe
Journal:  Drug Saf       Date:  1999-01       Impact factor: 5.606

5.  A blue kidney in a living donor.

Authors:  A J Mocelin; L Brandina; A M Fraga; P A Gordan; M R Bergonse; A M Matni; A L Guembarovski
Journal:  Transplantation       Date:  1987-07       Impact factor: 4.939

6.  Refractory anemia leading to renal hemosiderosis and renal failure.

Authors:  Sujatha Siddappa; K M Mythri; R Kowsalya; Ashish Parekh
Journal:  Indian J Pathol Microbiol       Date:  2011 Apr-Jun       Impact factor: 0.740

7.  On the degradability and exocytosis of ceroid/lipofuscin in cultured rat cardiac myocytes.

Authors:  A Terman; U T Brunk
Journal:  Mech Ageing Dev       Date:  1998-01-30       Impact factor: 5.432

8.  Lipofuscin accumulation in the vastus lateralis muscle in patients with chronic obstructive pulmonary disease.

Authors:  Joakim Allaire; François Maltais; Pierre LeBlanc; Pierre-Michel Simard; François Whittom; Jean-François Doyon; Clermont Simard; Jean Jobin
Journal:  Muscle Nerve       Date:  2002-03       Impact factor: 3.217

9.  Renal cell carcinoma with melanin pigment.

Authors:  Jayaprakash Shetty; Prabhu Laxman
Journal:  Indian J Urol       Date:  2010-04

10.  Tissue culture loading test with storage granules from animal models of neuronal ceroid-lipofuscinosis (Batten disease): testing their lysosomal degradability by normal and Batten cells.

Authors:  M Elleder; Z Drahota; V Lisá; V Mares; V Mandys; J Müller; D N Palmer
Journal:  Am J Med Genet       Date:  1995-06-05
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  1 in total

1.  A case report on lipofuscin deposition in a graft biopsy two years after kidney transplantation: an insignificant bystander or a pathogenic benefactor?

Authors:  Vivian W Y Leung; Sarah-Jeanne Pilon; Pierre O Fiset; Shaifali Sandal
Journal:  BMC Nephrol       Date:  2019-10-17       Impact factor: 2.388

  1 in total

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