Literature DB >> 24838472

Multifunctional theranostic red blood cells for magnetic-field-enhanced in vivo combination therapy of cancer.

Chao Wang1, Xiaoqi Sun, Liang Cheng, Shengnan Yin, Guangbao Yang, Yonggang Li, Zhuang Liu.   

Abstract

Red blood cells are attached to iron oxide nanoparticles pre-coated with chlorine e6, a photosensitizer, and then loaded with a chemotherapeutic drug, doxorubicin, to enable imaging-guided combined photodynamic and chemotherapy of cancer, achieving excellent synergistic therapeutic effects in an animal tumor model. This work highlights the great promise of integrating cell-based drug-delivery systems with nanotechnology as a biocompatible multifunctional platform for applications in cancer theranostics.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biomaterials; combination therapy; drug delivery; magnetic targeting; red blood cells

Mesh:

Substances:

Year:  2014        PMID: 24838472     DOI: 10.1002/adma.201400158

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  43 in total

1.  Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds.

Authors:  Flavia Fontana; Raquél Bartolo; Hélder A Santos
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Near Infrared Boron Dipyrromethene Nanoparticles for Optotheranostics.

Authors:  Ling Huang; Gang Han
Journal:  Small Methods       Date:  2018-07-25

3.  The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors.

Authors:  Mukaddes Izci; Christy Maksoudian; Bella B Manshian; Stefaan J Soenen
Journal:  Chem Rev       Date:  2021-01-14       Impact factor: 60.622

Review 4.  Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy.

Authors:  Lei Zhu; Zhiyang Zhou; Hui Mao; Lily Yang
Journal:  Nanomedicine (Lond)       Date:  2016-11-23       Impact factor: 5.307

Review 5.  In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles.

Authors:  Hamed Arami; Amit Khandhar; Denny Liggitt; Kannan M Krishnan
Journal:  Chem Soc Rev       Date:  2015-09-21       Impact factor: 54.564

6.  Red Blood Cell-Facilitated Photodynamic Therapy for Cancer Treatment.

Authors:  Wei Tang; Zipeng Zhen; Mengzhe Wang; Hui Wang; Yen-Jun Chuang; Weizhong Zhang; Geoffrey D Wang; Trever Todd; Taku Cowger; Hongmin Chen; Lin Liu; Zibo Li; Jin Xie
Journal:  Adv Funct Mater       Date:  2016-02-03       Impact factor: 18.808

Review 7.  Improving cell-based therapies by nanomodification.

Authors:  Wei Chen; Liwu Fu; Xiaoyuan Chen
Journal:  J Control Release       Date:  2015-09-28       Impact factor: 9.776

8.  Enhancing Photodynamic Therapy through Resonance Energy Transfer Constructed Near-Infrared Photosensitized Nanoparticles.

Authors:  Ling Huang; Zhanjun Li; Yang Zhao; Jinyi Yang; Yucheng Yang; Aarushi Iris Pendharkar; Yuanwei Zhang; Sharon Kelmar; Liyong Chen; Wenting Wu; Jianzhang Zhao; Gang Han
Journal:  Adv Mater       Date:  2017-06-06       Impact factor: 30.849

Review 9.  Harnessing Biology to Deliver Therapeutic and Imaging Entities via Cell-Based Methods.

Authors:  Bishnu P Joshi; Joseph Hardie; Michelle E Farkas
Journal:  Chemistry       Date:  2018-05-14       Impact factor: 5.236

10.  Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro.

Authors:  Hui-Ping Sun; Jing-Han Su; Qing-Shuo Meng; Qi Yin; Zhi-Wen Zhang; Hai-Jun Yu; Peng-Cheng Zhang; Si-Ling Wang; Ya-Ping Li
Journal:  Acta Pharmacol Sin       Date:  2016-05-02       Impact factor: 6.150

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