| Literature DB >> 24838472 |
Chao Wang1, Xiaoqi Sun, Liang Cheng, Shengnan Yin, Guangbao Yang, Yonggang Li, Zhuang Liu.
Abstract
Red blood cells are attached to iron oxide nanoparticles pre-coated with chlorine e6, a photosensitizer, and then loaded with a chemotherapeutic drug, doxorubicin, to enable imaging-guided combined photodynamic and chemotherapy of cancer, achieving excellent synergistic therapeutic effects in an animal tumor model. This work highlights the great promise of integrating cell-based drug-delivery systems with nanotechnology as a biocompatible multifunctional platform for applications in cancer theranostics.Entities:
Keywords: biomaterials; combination therapy; drug delivery; magnetic targeting; red blood cells
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Year: 2014 PMID: 24838472 DOI: 10.1002/adma.201400158
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849