Literature DB >> 24838168

Structural biology: a 'funny' cyclic dinucleotide receptor.

Yoni Haitin1.   

Abstract

Deciphering the molecular basis of HCN channel regulation by cGMP leads to the serendipitous discovery of cyclic dinucleotides as potent inhibitors of I(f) current in the heart.

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Year:  2014        PMID： 24838168     DOI： 10.1038/nchembio.1530

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


  7 in total

Review 1.  Cyclic dinucleotides and the innate immune response.

Authors:  Olga Danilchanka; John J Mekalanos
Journal:  Cell       Date:  2013-08-29       Impact factor: 41.582

2.  Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.

Authors:  Xin Li; Chang Shu; Guanghui Yi; Catherine T Chaton; Catherine L Shelton; Jiasheng Diao; Xiaobing Zuo; C Cheng Kao; Andrew B Herr; Pingwei Li
Journal:  Immunity       Date:  2013-12-12       Impact factor: 31.745

3.  Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.

Authors:  Marco Lolicato; Annalisa Bucchi; Cristina Arrigoni; Stefano Zucca; Marco Nardini; Indra Schroeder; Katie Simmons; Marco Aquila; Dario DiFrancesco; Martino Bolognesi; Frank Schwede; Dmitry Kashin; Colin W G Fishwick; A Peter Johnson; Gerhard Thiel; Anna Moroni
Journal:  Nat Chem Biol       Date:  2014-04-28       Impact factor: 15.040

4.  Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.

Authors:  Jiaxi Wu; Lijun Sun; Xiang Chen; Fenghe Du; Heping Shi; Chuo Chen; Zhijian J Chen
Journal:  Science       Date:  2012-12-20       Impact factor: 47.728

Review 5.  Cyclic di-GMP: the first 25 years of a universal bacterial second messenger.

Authors:  Ute Römling; Michael Y Galperin; Mark Gomelsky
Journal:  Microbiol Mol Biol Rev       Date:  2013-03       Impact factor: 11.056

6.  Structural basis for modulation and agonist specificity of HCN pacemaker channels.

Authors:  William N Zagotta; Nelson B Olivier; Kevin D Black; Edgar C Young; Rich Olson; Eric Gouaux
Journal:  Nature       Date:  2003-09-11       Impact factor: 49.962

Review 7.  CNG and HCN channels: two peas, one pod.

Authors:  Kimberley B Craven; William N Zagotta
Journal:  Annu Rev Physiol       Date:  2006       Impact factor: 19.318
  7 in total

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