Literature DB >> 24837098

Amino acids fuel T cell-mediated inflammation.

Maya C Poffenberger1, Russell G Jones2.   

Abstract

Reprogramming cellular metabolism helps support T cell growth and effector function upon activation. In this issue of Immunity, Nakaya et al. (2014) report that the glutamine transporter ASCT2 regulates T cell metabolism and mTOR kinase signaling to shape inflammatory T helper cell responses.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24837098     DOI： 10.1016/j.immuni.2014.04.017

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  13 in total

1.  Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis.

Authors:  Sivabalan Manivannan; Victoria K Baxter; Kimberly L W Schultz; Barbara S Slusher; Diane E Griffin
Journal:  J Virol       Date:  2016-09-29       Impact factor: 5.103

2.  Special Conference on Tumor Immunology and Immunotherapy: A New Chapter.

Authors:  Katelyn T Byrne; Robert H Vonderheide; Elizabeth M Jaffee; Todd D Armstrong
Journal:  Cancer Immunol Res       Date:  2015-05-12       Impact factor: 11.151

Review 3.  mTOR signaling, Tregs and immune modulation.

Authors:  Nicole M Chapman; Hongbo Chi
Journal:  Immunotherapy       Date:  2014       Impact factor: 4.196

4.  Metabolomic profile overlap in prototypical autoimmune humoral disease: a comparison of myasthenia gravis and rheumatoid arthritis.

Authors:  Derrick Blackmore; Liang Li; Nan Wang; Walter Maksymowych; Elaine Yacyshyn; Zaeem A Siddiqi
Journal:  Metabolomics       Date:  2020-01-04       Impact factor: 4.290

Review 5.  mTOR Links Environmental Signals to T Cell Fate Decisions.

Authors:  Nicole M Chapman; Hongbo Chi
Journal:  Front Immunol       Date:  2015-01-20       Impact factor: 7.561

Review 6.  Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease.

Authors:  Xianying Bao; Zemeng Feng; Jiming Yao; Tiejun Li; Yulong Yin
Journal:  Mediators Inflamm       Date:  2017-03-14       Impact factor: 4.711

Review 7.  The Human SLC1A5 (ASCT2) Amino Acid Transporter: From Function to Structure and Role in Cell Biology.

Authors:  Mariafrancesca Scalise; Lorena Pochini; Lara Console; Maria A Losso; Cesare Indiveri
Journal:  Front Cell Dev Biol       Date:  2018-09-04

8.  Lactic Acidosis Promotes Mitochondrial Biogenesis in Lung Adenocarcinoma Cells, Supporting Proliferation Under Normoxia or Survival Under Hypoxia.

Authors:  Susana Romero-Garcia; Heriberto Prado-Garcia; Alma Delia Valencia-Camargo; Abraham Alvarez-Pulido
Journal:  Front Oncol       Date:  2019-10-17       Impact factor: 6.244

9.  T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.

Authors:  Zeynep Sener; Fritjof H Cederkvist; Roman Volchenkov; Halvor L Holen; Bjørn S Skålhegg
Journal:  PLoS One       Date:  2016-07-28       Impact factor: 3.240

10.  Identification and characterization of a novel glutaminase inhibitor.

Authors:  Henning Cederkvist; Shrikant S Kolan; Jonas Aakre Wik; Zeynep Sener; Bjørn Steen Skålhegg
Journal:  FEBS Open Bio       Date:  2021-11-08       Impact factor: 2.693
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