Literature DB >> 24837097

p53 keeps bystanders at the gates.

Michael A Fray1, Stephen C Bunnell2.   

Abstract

The inappropriate expansion of self-reactive "bystander" T cells can contribute to autoimmune disease. In this issue of Immunity, Watanabe et al. (2014) demonstrate that the tumor suppressor p53 prevents the cytokine-dependent proliferation of T cells in the absence of cognate antigens.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24837097      PMCID： PMC6800040          DOI： 10.1016/j.immuni.2014.05.001

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  10 in total

1.  Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells.

Authors:  M C Haks; P Krimpenfort; J H van den Brakel; A M Kruisbeek
Journal:  Immunity       Date:  1999-07       Impact factor: 31.745

Review 2.  Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.

Authors:  Alfred Singer; Stanley Adoro; Jung-Hyun Park
Journal:  Nat Rev Immunol       Date:  2008-10       Impact factor: 53.106

3.  Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.

Authors:  Ineke den Braber; Tendai Mugwagwa; Nienke Vrisekoop; Liset Westera; Ramona Mögling; Anne Bregje de Boer; Neeltje Willems; Elise H R Schrijver; Gerrit Spierenburg; Koos Gaiser; Erik Mul; Sigrid A Otto; An F C Ruiter; Mariette T Ackermans; Frank Miedema; José A M Borghans; Rob J de Boer; Kiki Tesselaar
Journal:  Immunity       Date:  2012-02-24       Impact factor: 31.745

4.  V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

Authors:  C J Guidos; C J Williams; I Grandal; G Knowles; M T Huang; J S Danska
Journal:  Genes Dev       Date:  1996-08-15       Impact factor: 11.361

5.  Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells.

Authors:  Hirotoshi Kawashima; Hiroaki Takatori; Kotaro Suzuki; Arifumi Iwata; Masaya Yokota; Akira Suto; Tohru Minamino; Koichi Hirose; Hiroshi Nakajima
Journal:  J Immunol       Date:  2013-09-04       Impact factor: 5.422

6.  Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responses.

Authors:  Masashi Watanabe; Kyung Duk Moon; Melanie S Vacchio; Karen S Hathcock; Richard J Hodes
Journal:  Immunity       Date:  2014-05-01       Impact factor: 31.745

7.  The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells.

Authors:  Ryan T Phan; Riccardo Dalla-Favera
Journal:  Nature       Date:  2004-12-02       Impact factor: 49.962

8.  Interleukin-7 supports survival of T-cell receptor-β-expressing CD4(-) CD8(-) double-negative thymocytes.

Authors:  Juan Xiong; Brooks L Parker; Stacy L Dalheimer; Thomas M Yankee
Journal:  Immunology       Date:  2013-04       Impact factor: 7.397

Review 9.  Cytoplasmic functions of the tumour suppressor p53.

Authors:  Douglas R Green; Guido Kroemer
Journal:  Nature       Date:  2009-04-30       Impact factor: 49.962

Review 10.  Modes of p53 regulation.

Authors:  Jan-Philipp Kruse; Wei Gu
Journal:  Cell       Date:  2009-05-15       Impact factor: 41.582
  10 in total
  2 in total

1.  Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.

Authors:  Kyoung Wan Yoon; Sanguine Byun; Eunjeong Kwon; So-Young Hwang; Kiki Chu; Masatsugu Hiraki; Seung-Hee Jo; Astrid Weins; Samy Hakroush; Angelika Cebulla; David B Sykes; Anna Greka; Peter Mundel; David E Fisher; Anna Mandinova; Sam W Lee
Journal:  Science       Date:  2015-07-31       Impact factor: 47.728

2.  Loss of Perp in T Cells Promotes Resistance to Apoptosis of T Helper 17 Cells and Exacerbates the Development of Experimental Autoimmune Encephalomyelitis in Mice.

Authors:  Yan Zhou; Xiao Leng; Yan He; Yan Li; Yuan Liu; Yang Liu; Qiang Zou; Guixiu Shi; Yantang Wang
Journal:  Front Immunol       Date:  2018-04-23       Impact factor: 7.561
  2 in total

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