Literature DB >> 24836127

Palladium catalyzed C3-arylation of 4-hydroxy-2-pyridones.

Elissavet E Anagnostaki1, Anna D Fotiadou, Vera Demertzidou, Alexandros L Zografos.   

Abstract

The direct arylation of N-substituted-4-hydroxy-2-pyridones with aryl boronic acids has been achieved under palladium catalysis. The mild reaction conditions applied in this method and the use of a conventional catalytic system offer an attractive protocol for the efficient synthesis of a variety of 3-arylated products.

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Year:  2014        PMID: 24836127     DOI: 10.1039/c4cc02166e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  A lesson for site-selective C-H functionalization on 2-pyridones: radical, organometallic, directing group and steric controls.

Authors:  Koji Hirano; Masahiro Miura
Journal:  Chem Sci       Date:  2017-11-27       Impact factor: 9.825

2.  Cobalt(iii)-catalyzed site-selective C-H amidation of pyridones and isoquinolones.

Authors:  Feng Gao; Xu Han; Chunpu Li; Lingjun Liu; Zhanqing Cong; Hong Liu
Journal:  RSC Adv       Date:  2018-09-21       Impact factor: 3.361

3.  Ru(ii)-catalyzed C6-selective C-H acylmethylation of pyridones using sulfoxonium ylides as carbene precursors.

Authors:  Yangjie Fu; Zhaohui Wang; Qiyu Zhang; Zhiyu Li; Hong Liu; Xiaoling Bi; Jiang Wang
Journal:  RSC Adv       Date:  2020-02-11       Impact factor: 4.036

4.  Rhodium(i)-catalyzed C6-selective C-H alkenylation and polyenylation of 2-pyridones with alkenyl and conjugated polyenyl carboxylic acids.

Authors:  Haoqiang Zhao; Xin Xu; Zhenli Luo; Lei Cao; Bohan Li; Huanrong Li; Lijin Xu; Qinghua Fan; Patrick J Walsh
Journal:  Chem Sci       Date:  2019-09-09       Impact factor: 9.825

  4 in total

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