Maria J Teran-Alonso1, Javier De Santiago2, Ramon Usandizaga2, Ignacio Zapardiel3. 1. Gynecology Unit, Hospital Sanitas La Moraleja, Madrid, Spain. 2. Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain. 3. Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain. Electronic address: ignaciozapardiel@hotmail.com.
Abstract
OBJECTIVE: To evaluate whether administration of analgesic medication one hour before undergoing office hysteroscopy decreased pain and other side effects. STUDY DESIGN: A prospective randomized study was carried out in 200 patients who underwent office hysteroscopy from November 2011 until May 2012. 100 patients received1000 mg paracetamol and 600 mg ibuprofen one hour before the procedure and 100 did not receive any medication. RESULTS: We observed significant differences (p = 0.013) regarding the occurrence of non-pain side effects, 6% in the non-medicated group and none of the patients in the medicated group. The main pain score was always slightly higher in the group receiving no medication, though there was no statistically significant difference when compared to the medicated group. CONCLUSION: Administration of 1 g paracetamol and 600 mg ibuprofen one hour prior to office hysteroscopy decreased statistically the occurrence of non-pain side effects such as nausea, emesis, and hypotension. No differences in pain scores were observed.
RCT Entities:
OBJECTIVE: To evaluate whether administration of analgesic medication one hour before undergoing office hysteroscopy decreased pain and other side effects. STUDY DESIGN: A prospective randomized study was carried out in 200 patients who underwent office hysteroscopy from November 2011 until May 2012. 100 patients received 1000 mg paracetamol and 600 mg ibuprofen one hour before the procedure and 100 did not receive any medication. RESULTS: We observed significant differences (p = 0.013) regarding the occurrence of non-pain side effects, 6% in the non-medicated group and none of the patients in the medicated group. The main pain score was always slightly higher in the group receiving no medication, though there was no statistically significant difference when compared to the medicated group. CONCLUSION: Administration of 1 g paracetamol and 600 mg ibuprofen one hour prior to office hysteroscopy decreased statistically the occurrence of non-pain side effects such as nausea, emesis, and hypotension. No differences in pain scores were observed.
Authors: Giovanni Buzzaccarini; Luis Alonso Pacheco; Amerigo Vitagliano; Sergio Haimovich; Vito Chiantera; Péter Török; Salvatore Giovanni Vitale; Antonio Simone Laganà; Jose Carugno Journal: Medicina (Kaunas) Date: 2022-08-20 Impact factor: 2.948