Literature DB >> 24835616

Private predictive analysis on encrypted medical data.

Joppe W Bos1, Kristin Lauter2, Michael Naehrig1.   

Abstract

Increasingly, confidential medical records are being stored in data centers hosted by hospitals or large companies. As sophisticated algorithms for predictive analysis on medical data continue to be developed, it is likely that, in the future, more and more computation will be done on private patient data. While encryption provides a tool for assuring the privacy of medical information, it limits the functionality for operating on such data. Conventional encryption methods used today provide only very restricted possibilities or none at all to operate on encrypted data without decrypting it first. Homomorphic encryption provides a tool for handling such computations on encrypted data, without decrypting the data, and without even needing the decryption key. In this paper, we discuss possible application scenarios for homomorphic encryption in order to ensure privacy of sensitive medical data. We describe how to privately conduct predictive analysis tasks on encrypted data using homomorphic encryption. As a proof of concept, we present a working implementation of a prediction service running in the cloud (hosted on Microsoft's Windows Azure), which takes as input private encrypted health data, and returns the probability for suffering cardiovascular disease in encrypted form. Since the cloud service uses homomorphic encryption, it makes this prediction while handling only encrypted data, learning nothing about the submitted confidential medical data.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Encrypted medical data; Homomorphic encryption; Logistic regression; Predictive analysis; Proportional hazard model

Mesh:

Year:  2014        PMID: 24835616     DOI: 10.1016/j.jbi.2014.04.003

Source DB:  PubMed          Journal:  J Biomed Inform        ISSN: 1532-0464            Impact factor:   6.317


  24 in total

1.  Core Concept: Homomorphic encryption.

Authors:  Robert Frederick
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-14       Impact factor: 11.205

2.  Privacy-preserving biomedical data dissemination via a hybrid approach.

Authors:  Yichen Jiang; Chenghong Wang; Zhixuan Wu; Xin Du; Shuang Wang
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05

3.  PREMIX: PRivacy-preserving EstiMation of Individual admiXture.

Authors:  Feng Chen; Michelle Dow; Sijie Ding; Yao Lu; Xiaoqian Jiang; Hua Tang; Shuang Wang
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

4.  SCOTCH: Secure Counting Of encrypTed genomiC data using a Hybrid approach.

Authors:  Wang Chenghong; Yichen Jiang; Noman Mohammed; Feng Chen; Xiaoqian Jiang; Md Momin Al Aziz; Md Nazmus Sadat; Shuang Wang
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

5.  Protecting genomic data analytics in the cloud: state of the art and opportunities.

Authors:  Haixu Tang; Xiaoqian Jiang; Xiaofeng Wang; Shuang Wang; Heidi Sofia; Dov Fox; Kristin Lauter; Bradley Malin; Amalio Telenti; Li Xiong; Lucila Ohno-Machado
Journal:  BMC Med Genomics       Date:  2016-10-13       Impact factor: 3.063

Review 6.  Privacy-preserving techniques of genomic data-a survey.

Authors:  Md Momin Al Aziz; Md Nazmus Sadat; Dima Alhadidi; Shuang Wang; Xiaoqian Jiang; Cheryl L Brown; Noman Mohammed
Journal:  Brief Bioinform       Date:  2019-05-21       Impact factor: 11.622

7.  State of the art and a mixed-method personalized approach to assess patient perceptions on medical record sharing and sensitivity.

Authors:  Hiral Soni; Adela Grando; Anita Murcko; Sabrina Diaz; Madhumita Mukundan; Nassim Idouraine; George Karway; Michael Todd; Darwyn Chern; Christy Dye; Mary Jo Whitfield
Journal:  J Biomed Inform       Date:  2019-11-11       Impact factor: 6.317

8.  Private and Efficient Query Processing on Outsourced Genomic Databases.

Authors:  Reza Ghasemi; Md Momin Al Aziz; Noman Mohammed; Massoud Hadian Dehkordi; Xiaoqian Jiang
Journal:  IEEE J Biomed Health Inform       Date:  2016-11-04       Impact factor: 5.772

9.  Privacy Policy and Technology in Biomedical Data Science.

Authors:  April Moreno Arellano; Wenrui Dai; Shuang Wang; Xiaoqian Jiang; Lucila Ohno-Machado
Journal:  Annu Rev Biomed Data Sci       Date:  2018-07

10.  HEALER: homomorphic computation of ExAct Logistic rEgRession for secure rare disease variants analysis in GWAS.

Authors:  Shuang Wang; Yuchen Zhang; Wenrui Dai; Kristin Lauter; Miran Kim; Yuzhe Tang; Hongkai Xiong; Xiaoqian Jiang
Journal:  Bioinformatics       Date:  2015-10-06       Impact factor: 6.937

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