Literature DB >> 24834989

Randomly arrayed G-quadruplexes for label-free and real-time assay of enzyme activity.

Zhuoliang Liu1, Wang Li, Zhou Nie, Feifei Peng, Yan Huang, Shouzhuo Yao.   

Abstract

Randomly arrayed G-quadruplexes can serve as an efficient peroxidase-mimic DNAzyme and provide a novel and facile method to detect terminal deoxynucleotidyl transferase (TdT). Moreover, this G-rich sequence binding to the thioflavin T (ThT) dye can be applied in real-time fluorescent detection of TdT activity.

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Year:  2014        PMID： 24834989     DOI： 10.1039/c4cc03103b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

1.  Fluorometric determination of the activity of the biomarker terminal deoxynucleotidyl transferase via the enhancement of the fluorescence of silver nanoclusters by in-situ grown DNA tails.

Authors:  Bao-Zhu Chi; Chen-Lu Wang; Zhi-Qiao Wang; Ting Pi; Xiao-Li Zhong; Chao-Qun Deng; Yu-Chuan Feng; Zhi-Mei Li
Journal:  Mikrochim Acta       Date:  2019-03-13       Impact factor: 5.833

2.  Luminescence determination of microRNAs based on the use of terbium(III) sensitized with an enzyme-activated guanine-rich nucleotide.

Authors:  Bao-Zhu Chi; Ru-Ping Liang; Yan-Hong Yuan; Li Zhang; Zhi-Mei Li; Jian-Ding Qiu
Journal:  Mikrochim Acta       Date:  2018-05-03       Impact factor: 5.833

3.  The Cholesterol-Lowering Effect of Alisol Acetates Based on HMG-CoA Reductase and Its Molecular Mechanism.

Authors:  Fei Xu; Hui Yu; Cai Lu; Jun Chen; Wei Gu
Journal:  Evid Based Complement Alternat Med       Date:  2016-10-30       Impact factor: 2.629

4.  A rapid and visual turn-off sensor for detecting copper (II) ion based on DNAzyme coupled with HCR-based HRP concatemers.

Authors:  Wentao Xu; Jingjing Tian; Yunbo Luo; Longjiao Zhu; Kunlun Huang
Journal:  Sci Rep       Date:  2017-03-07       Impact factor: 4.379

5.  Harnessing a previously unidentified capability of bacterial allosteric transcription factors for sensing diverse small molecules in vitro.

Authors:  Jiaqian Cao; Yongpeng Yao; Keqiang Fan; Gaoyi Tan; Wensheng Xiang; Xuekui Xia; Shanshan Li; Weishan Wang; Lixin Zhang
Journal:  Sci Adv       Date:  2018-11-28       Impact factor: 14.136

6.  An ultrasensitive flow cytometric immunoassay based on bead surface-initiated template-free DNA extension.

Authors:  Liping Zhu; Desheng Chen; Xiaohui Lu; Yan Qi; Pan He; Chenghui Liu; Zhengping Li
Journal:  Chem Sci       Date:  2018-07-23       Impact factor: 9.825

7.  Optimization of Gonyautoxin1/4-Binding G-Quadruplex Aptamers by Label-Free Surface-Enhanced Raman Spectroscopy.

Authors:  Yan Liu; Chengshun Jiang; Menghua Song; Yongbing Cao; Qiang Huang; Feng Lu
Journal:  Toxins (Basel)       Date:  2022-09-06       Impact factor: 5.075

8.  Insight into G-quadruplex-hemin DNAzyme/RNAzyme: adjacent adenine as the intramolecular species for remarkable enhancement of enzymatic activity.

Authors:  Wang Li; Yong Li; Zhuoliang Liu; Bin Lin; Haibo Yi; Feng Xu; Zhou Nie; Shouzhuo Yao
Journal:  Nucleic Acids Res       Date:  2016-07-15       Impact factor: 16.971

9.  Thioflavin T binds dimeric parallel-stranded GA-containing non-G-quadruplex DNAs: a general approach to lighting up double-stranded scaffolds.

Authors:  Shuangna Liu; Pai Peng; Huihui Wang; Lili Shi; Tao Li
Journal:  Nucleic Acids Res       Date:  2017-12-01       Impact factor: 16.971

10.  Simultaneous Monitoring of Cell-surface Receptor and Tumor-targeted Photodynamic Therapy via TdT-initiated Poly-G-Quadruplexes.

Authors:  Tianhui Shi; Menglin Wang; Hao Li; Miao Wang; Xingyu Luo; Yan Huang; Hong-Hui Wang; Zhou Nie; Shouzhuo Yao
Journal:  Sci Rep       Date:  2018-04-03       Impact factor: 4.379
  10 in total

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