Literature DB >> 24833198

Orf disease: a report of a case.

Theocharis Koufakis1, Periklis Katsaitis2, Ioannis Gabranis3.   

Abstract

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Year:  2014        PMID: 24833198      PMCID: PMC9428213          DOI: 10.1016/j.bjid.2014.04.001

Source DB:  PubMed          Journal:  Braz J Infect Dis        ISSN: 1413-8670            Impact factor:   3.257


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A 19 year-old Caucasian male shepherd, with no relevant medical history, presented to the Emergency Department of our hospital complaining about a necrotic lesion at the dorsal surface of his left hand (Fig. 1A). He mentioned that he had noticed similar lesions located at the lips and the breasts of his sheep (Fig. 1B). The diagnosis of Orf disease was clinically established, based on the typical presentation and the positive history of exposure. No special treatment was given to the patient, apart from local antiseptics, resulting in complete regression of the lesions within a month period. He was strongly advised to wear gloves when handling his animals and practice proper hand hygiene. Orf (or Contagious Ecthyma) is a zoonotic disease, caused by a parapoxvirus and mainly affects sheep and goats, but it can be transmitted to humans through direct contact with infected animals. It is generally considered as a self-limited clinical entity. However, successful treatment of complicated cases with topical use of imiquimod or cidofovir cream has been described in the literature.
Fig. 1

(A) Orf lesions located at the patient's hand and (B) at the breasts of his sheep.

(A) Orf lesions located at the patient's hand and (B) at the breasts of his sheep.

Conflicts of interest

The authors declare no conflicts of interest.
  4 in total

1.  Orf (contagious pustular dermatitis) in farmworkers: prevalence and risk factors in three areas of England.

Authors:  G A Paiba; D R Thomas; K L Morgan; M Bennett; R L Salmon; R Chalmers; S M Kench; T J Coleman; D Meadows; P Morgan-Capner; P Softley; M Sillis; L E Green
Journal:  Vet Rec       Date:  1999-07-03       Impact factor: 2.695

2.  A case of human orf in an immunocompromised patient treated successfully with cidofovir cream.

Authors:  K Geerinck; G Lukito; R Snoeck; R De Vos; E De Clercq; Y Vanrenterghem; H Degreef; B Maes
Journal:  J Med Virol       Date:  2001-08       Impact factor: 2.327

3.  Rapid improvement of human orf (ecthyma contagiosum) with topical imiquimod cream: report of four complicated cases.

Authors:  Zülal Erbağci; Ibrahim Erbağci; A Almila Tuncel
Journal:  J Dermatolog Treat       Date:  2005       Impact factor: 3.359

4.  Human orf and milkers' nodule: a clinicopathologic study.

Authors:  R W Groves; E Wilson-Jones; D M MacDonald
Journal:  J Am Acad Dermatol       Date:  1991-10       Impact factor: 11.527

  4 in total
  3 in total

1.  A Case of Orf Disease Complicated with Erythema Multiforme and Bullous Pemphigoid-Like Eruptions.

Authors:  Shahriar Alian; Fatemeh Ahangarkani; Sara Arabsheybani
Journal:  Case Rep Infect Dis       Date:  2015-07-29

Review 2.  A Review on Human Orf: A Neglected Viral Zoonosis.

Authors:  Tesfaye Kassa
Journal:  Res Rep Trop Med       Date:  2021-07-08

3.  Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia.

Authors:  Mebrahtu Tedla; Nega Berhan; Wassie Molla; Wudu Temesgen; Sefinew Alemu
Journal:  BMC Vet Res       Date:  2018-01-15       Impact factor: 2.741

  3 in total

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