Haibo Jiang1, Xiaobin Cao2, Changhe Wang2, Wei Luo2, Jianhua Li3, Keming Rou2, Bo Zhang3, Yuehua Fang4, Cong Li5, Zunyou Wu6. 1. School of Public Health, Anhui Medical University, Hefei 230032, China; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. 2. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. 3. Yunnan Institute for Drug Abuse. 4. Dali City Center for Disease Control and Prevention. 5. Dali Prefecture No. 2nd People's Hospital. 6. School of Public Health, Anhui Medical University, Hefei 230032, China; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. Email: wuzy@263.net.
Abstract
OBJECTIVE: To describe the adherence and related determinants among HIV-positive methadone maintenance treatment(MMT)clients in Dali,Yunnan province from 2005 to 2013. METHODS: Cases were selected from the "National MMT Information Management System". The main information included demographic, drug abuse behaviors prior to enrollment, MMT treatment and highly active antiretroviral therapy (HAART). Detailed medication records were collected to calculate the adherence to MMT. Multivariate unconditional logistic regression was conducted to analyze the impact factors of adherence. RESULTS: The MMT adherence rate of 480 subjects is 58.11%. Data from the multivariate unconditional logistic regression indicated that among those HIV-positive MMT clients that on HAART program (OR = 1.52, 95% CI:1.03-2.24), related factors as:having stable job(OR = 1.69, 95% CI:1.11-2.56), having compulsory history prior to enrollment in MMT (OR = 1.78, 95% CI:1.04-3.04) were likely to have higher rate on MMT adherence, whereas clients who showed positive result in the last urine morphine test (OR = 0.38, 95% CI:0.24-0.59) were associated with lower rate on MMT adherence. CONCLUSION: In order to improve the rate of adherence to MMT among those HIV-positive MMT clients, the coverage of HAART needed to be expanded and new approaches in combining MMT and HAART developed. Education and intervention efforts should be focused on clients who currently were jobless, those with last urine morphine testing as positive or had never received compulsory treatment.
OBJECTIVE: To describe the adherence and related determinants among HIV-positive methadone maintenance treatment(MMT)clients in Dali,Yunnan province from 2005 to 2013. METHODS: Cases were selected from the "National MMT Information Management System". The main information included demographic, drug abuse behaviors prior to enrollment, MMT treatment and highly active antiretroviral therapy (HAART). Detailed medication records were collected to calculate the adherence to MMT. Multivariate unconditional logistic regression was conducted to analyze the impact factors of adherence. RESULTS: The MMT adherence rate of 480 subjects is 58.11%. Data from the multivariate unconditional logistic regression indicated that among those HIV-positive MMT clients that on HAART program (OR = 1.52, 95% CI:1.03-2.24), related factors as:having stable job(OR = 1.69, 95% CI:1.11-2.56), having compulsory history prior to enrollment in MMT (OR = 1.78, 95% CI:1.04-3.04) were likely to have higher rate on MMT adherence, whereas clients who showed positive result in the last urine morphine test (OR = 0.38, 95% CI:0.24-0.59) were associated with lower rate on MMT adherence. CONCLUSION: In order to improve the rate of adherence to MMT among those HIV-positive MMT clients, the coverage of HAART needed to be expanded and new approaches in combining MMT and HAART developed. Education and intervention efforts should be focused on clients who currently were jobless, those with last urine morphine testing as positive or had never received compulsory treatment.
Authors: En Chao; Chia-Chun Hung; Ching-Po Lin; Yi-Chien Jacob Ku; Qurat Ul Ain; David S Metzger; Tony Szu-Hsien Lee Journal: BMC Psychiatry Date: 2020-07-02 Impact factor: 3.630