CONTEXT: Systemic sclerosis (SSc) is an autoimmune disease with incompletely known physiopathology. There is a great challenge to predict its course and therapeutic response using biomarkers. OBJECTIVE: To critically review proteomic biomarkers discovered from biological specimens from systemic sclerosis patients using mass spectrometry technologies. METHODS: Medline and Embase databases were searched in February 2014. RESULTS: Out of the 199 records retrieved, a total of 20 records were included, identifying 116 candidate proteomic biomarkers. CONCLUSION: Research in SSc proteomic biomarkers should focus on biomarker validation, as there are valuable mass-spectrometry proteomics studies in the literature.
CONTEXT: Systemic sclerosis (SSc) is an autoimmune disease with incompletely known physiopathology. There is a great challenge to predict its course and therapeutic response using biomarkers. OBJECTIVE: To critically review proteomic biomarkers discovered from biological specimens from systemic sclerosispatients using mass spectrometry technologies. METHODS: Medline and Embase databases were searched in February 2014. RESULTS: Out of the 199 records retrieved, a total of 20 records were included, identifying 116 candidate proteomic biomarkers. CONCLUSION: Research in SSc proteomic biomarkers should focus on biomarker validation, as there are valuable mass-spectrometry proteomics studies in the literature.
Authors: Paul Bălănescu; Anca Lădaru; Eugenia Bălănescu; Theodor Voiosu; Cristian Băicuş; Gheorghe Andrei Dan Journal: J Clin Lab Anal Date: 2015-09-01 Impact factor: 2.352
Authors: Ryan T Kendall; Ludivine Renaud; John E Baatz; Maya Malaab; Xinh-Xinh Nguyen; Carol A Feghali-Bostwick Journal: J Proteomics Date: 2021-04-27 Impact factor: 3.855
Authors: Paraskevi Chairta; Paschalis Nicolaou; Kleitos Sokratous; Christine Galant; Frédéric Houssiau; Anastasis Oulas; George M Spyrou; Marta E Alarcon-Riquelme; Bernard R Lauwerys; Kyproula Christodoulou Journal: Arthritis Res Ther Date: 2020-05-07 Impact factor: 5.156