Literature DB >> 24830507

Multivalent comb-type aptamer-siRNA conjugates for efficient and selective intracellular delivery.

Hyundong Yoo1, Hyosook Jung, Seung An Kim, Hyejung Mok.   

Abstract

In this study, a simple and efficient strategy for selective intracellular delivery of RNA therapeutics into target cancer cells was designed using direct complementary base pairing between chemically conjugated multimeric antisense strands and aptamer-incorporating sense strands.

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Year:  2014        PMID： 24830507     DOI： 10.1039/c4cc01620c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  An in Vitro Selection Strategy Identifying Naked DNA That Localizes to Cell Nuclei.

Authors:  John Smestad; Brandon Wilbanks; Louis J Maher
Journal:  J Am Chem Soc       Date:  2019-11-12       Impact factor: 15.419

Review 2.  Aptamer-Based Cancer Cell Analysis and Treatment.

Authors:  Limei Wu; Yutong Zhang; Zhimin Wang; Yue Zhang; Jianmei Zou; Liping Qiu
Journal:  ChemistryOpen       Date:  2022-10       Impact factor: 2.630

3.  Direct oligonucleotide-photosensitizer conjugates for photochemical delivery of antisense oligonucleotides.

Authors:  Ahu Yuan; Brian Laing; Yiqiao Hu; Xin Ming
Journal:  Chem Commun (Camb)       Date:  2015-04-18       Impact factor: 6.222

Review 4.  Aptamer-mediated selective delivery of short RNA therapeutics in cancer cells.

Authors:  Carla Lucia Esposito; Silvia Catuogno; Vittorio de Franciscis
Journal:  J RNAi Gene Silencing       Date:  2014-10-30

Review 5.  Aptamer technology for tracking cells' status & function.

Authors:  Christian Wiraja; David Yeo; Daniel Lio; Louai Labanieh; Mengrou Lu; Weian Zhao; Chenjie Xu
Journal:  Mol Cell Ther       Date:  2014-10-27

Review 6.  Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy.

Authors:  Lukas J Aaldering; Hossam Tayeb; Shilpa Krishnan; Susan Fletcher; Stephen D Wilton; Rakesh N Veedu
Journal:  RNA Biol       Date:  2015       Impact factor: 4.652

Review 7.  Multimeric RNAs for efficient RNA-based therapeutics and vaccines.

Authors:  Dajeong Kim; Sangwoo Han; Yoonbin Ji; Sunghyun Moon; Hyangsu Nam; Jong Bum Lee
Journal:  J Control Release       Date:  2022-03-31       Impact factor: 11.467

8.  Multimerized self-assembled caged two-in-one siRNA nanoparticles for photomodulation of RNAi-induced gene silencing.

Authors:  Changmai Chen; Nannan Jing; Zhongyu Wang; Yu Zhang; Wei Chen; Xinjing Tang
Journal:  Chem Sci       Date:  2020-10-12       Impact factor: 9.825

Review 9.  Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates.

Authors:  Santiago Grijalvo; Adele Alagia; Andreia F Jorge; Ramon Eritja
Journal:  Genes (Basel)       Date:  2018-02-06       Impact factor: 4.096

Review 10.  Multivalent Aptamer Approach: Designs, Strategies, and Applications.

Authors:  Zhong Wang; Xiuying Yang; Nicholas Zhou Lee; Xudong Cao
Journal:  Micromachines (Basel)       Date:  2022-03-12       Impact factor: 2.891
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