Anjali Mishra1, Prateek Kumar Mehrotra, Gaurav Agarwal, Amit Agarwal, Saroj Kanta Mishra. 1. Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, UP, India. Correspondence to: Dr Anjali Mishra, Additional Professor, Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226 014, India. anjali@sgpgi.ac.in.
Abstract
OBJECTIVES: To describe the clinical presentation and outcome of surgery in children with pheochromocytoma in a tertiary care hospital in India. METHODS: Clinical records of 24 children who were operated between January 1990 and January 2011 were reviewed. The diagnosis of familial disease was established based on clinical examination and follow-up events. RESULTS: Familial, bilateral, extra-adrenal and malignant pheochromocytoma were observed in 20.8%, 20.8%, 12.5% and 4.2% children, respectively. Median follow-up duration was 36 months. Persistent hypertension was noted in 12.5% patients and similar proportion died in follow-up. CONCLUSIONS: In the absence of routine genetic screening, good history and long- term follow up are essential to rule out familial pheochromocytoma.
OBJECTIVES: To describe the clinical presentation and outcome of surgery in children with pheochromocytoma in a tertiary care hospital in India. METHODS: Clinical records of 24 children who were operated between January 1990 and January 2011 were reviewed. The diagnosis of familial disease was established based on clinical examination and follow-up events. RESULTS: Familial, bilateral, extra-adrenal and malignant pheochromocytoma were observed in 20.8%, 20.8%, 12.5% and 4.2% children, respectively. Median follow-up duration was 36 months. Persistent hypertension was noted in 12.5% patients and similar proportion died in follow-up. CONCLUSIONS: In the absence of routine genetic screening, good history and long- term follow up are essential to rule out familial pheochromocytoma.
Authors: Martin K Walz; Laura D Iova; Judith Deimel; Hartmut P H Neumann; Birke Bausch; Stefan Zschiedrich; Harald Groeben; Pier F Alesina Journal: World J Surg Date: 2018-04 Impact factor: 3.352