V K Sharma1, D Raj, I Xess, R Lodha, S K Kabra. 1. Department of Pediatrics and * Microbiology, All India Institute of Medical Sciences, New Delhi, India. Correspondence to: Dr Varun K Sharma, Senior Resident, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110 029, India. drvarun1983@gmail.com.
Abstract
OBJECTIVES: Allergic bronchopulmonary aspergillosis (ABPA) is a common complication in patients with cystic fibrosis. This cross-sectional study was planned to determine the prevalence and risk factors for ABPA in Indian children with cystic fibrosis. METHODS: Clinical evaluation, spirometry, chest radiograph, sputum, total IgE, specific IgE for Aspergillus fumigatus, IgG precipitins and skin prick tests were done in 33 CF patients. RESULTS: Prevalence of allergic bronchopulmonary aspergillosis was 18.2% (95% CI 6.9% - 35.4%): allergic bronchopulmonary aspergillosis was higher in patients with low cystic fibrosis score, age >12 years, atopy, and eosinophilia. CONCLUSION: Prevalence of ABPA is higher in Indian children with cystic fibrosis.
OBJECTIVES:Allergic bronchopulmonary aspergillosis (ABPA) is a common complication in patients with cystic fibrosis. This cross-sectional study was planned to determine the prevalence and risk factors for ABPA in Indian children with cystic fibrosis. METHODS: Clinical evaluation, spirometry, chest radiograph, sputum, total IgE, specific IgE for Aspergillus fumigatus, IgG precipitins and skin prick tests were done in 33 CFpatients. RESULTS: Prevalence of allergic bronchopulmonary aspergillosis was 18.2% (95% CI 6.9% - 35.4%): allergic bronchopulmonary aspergillosis was higher in patients with low cystic fibrosis score, age >12 years, atopy, and eosinophilia. CONCLUSION: Prevalence of ABPA is higher in Indian children with cystic fibrosis.