Thowfique K Ibrahim1, A A Abdul Haium, S Chandran, V S Rajadurai. 1. Correspondence to: Victor Samuel Rajadurai, Head of Department of Neonatology, KK Women's and Childrens Hospital, 100 Bukit Timah Road, Singapore 229899. victor.samuel@kkh.com.sg.
Abstract
OBJECTIVE: Patent ductus arteriosus is very commonly seen in very low birth weight (VLBW) infants, affecting about one-third. The present review tries to identify the group of VLBW infants who need active intervention in day-to-day practice and to determine the mode of intervention, based on current published literatures. METHODS: We searched the Cochrane library, MEDLINE, EMBASE and CINAHL databases, and reference that of identified trials. RESULTS AND CONCLUSIONS: Preterm infants with a birth weight of <800g are at risk of significant morbidity and mortality from PDA; it would be reasonable to treat them when symptomatic or if requiring positive pressure ventilator support. Those weighing >800g are unlikely to need treatment unless they are ventilator-dependent or show evidence of congestive heart failure.
OBJECTIVE: Patent ductus arteriosus is very commonly seen in very low birth weight (VLBW) infants, affecting about one-third. The present review tries to identify the group of VLBW infants who need active intervention in day-to-day practice and to determine the mode of intervention, based on current published literatures. METHODS: We searched the Cochrane library, MEDLINE, EMBASE and CINAHL databases, and reference that of identified trials. RESULTS AND CONCLUSIONS: Preterm infants with a birth weight of <800g are at risk of significant morbidity and mortality from PDA; it would be reasonable to treat them when symptomatic or if requiring positive pressure ventilator support. Those weighing >800g are unlikely to need treatment unless they are ventilator-dependent or show evidence of congestive heart failure.
Authors: Thowfique Ibrahim; Abdul Alim Abdul Haium; Sarah Jane Tapawan; Rowena Dela Puerta; John C Allen; Suresh Chandran; Mei Chien Chua; Victor Samuel Rajadurai Journal: Front Pediatr Date: 2021-01-28 Impact factor: 3.418